Apoptosis of HL-60 leukemia cells induced by the bisindole alkaloids sungucine and isosungucine from Strychnos icaja

Planta Medica

Volumn 68, Issue 7, 2002, Pages 591-595

  Lansiaux, Amélie ^a   Bailly, Christian ^a   Houssier, Claude ^b   Colson, Pierre ^b   De Pauw Gillet, Marie Claire ^b   Frédérich, Michel ^b   Tits, Monique ^b   Angenot, Luc ^b  

^a CENTRE OSCAR LAMBRET   (France)

^b UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

Apoptosis; DNA binding; DNA synthesis; Isosungucine; Loganiaceae; Plant alkaloids; Strychnos icaja; Sungucine

Indexed keywords

ALKALOID DERIVATIVE; CASPASE 3; ISOSUNGUCINE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; SUNGUCINE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL DEATH; CELL STRAIN HL 60; CONTROLLED STUDY; DNA CONTENT; HUMAN; HUMAN CELL; NICK END LABELING; PHYTOCHEMISTRY;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CASPASE 3; CASPASES; CELL CYCLE; CHROMATIN; DNA; DNA FRAGMENTATION; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME ACTIVATION; HL-60 CELLS; HUMANS; INDOLE ALKALOIDS; LEUKEMIA; LOGANIACEAE; NUCLEIC ACID SYNTHESIS INHIBITORS; PROTEIN SYNTHESIS INHIBITORS; STRYCHNINE;

LOGANIACEAE; STRYCHNOS; STRYCHNOS ICAJA;

EID: 0036315776     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2002-32889     Document Type: Article

References (9)

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4. African species of Strychnos. Part 1. The ethnobotany
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6. Investigating nucleic acids, nucleoproteins, polynucleotides, and their interactions with small ligands by electro-optical systems
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