Mechanisms of action of the 5-HT 1B/1D receptor agonists

Archives of Neurology

Volumn 59, Issue 7, 2002, Pages 1084-1088

  Tepper, Stewart J ^a,b,d,e,f,g   Rapoport, Alan M ^{a,b,d,e,f,g,h,i,j,k}   Sheftell, Fred D ^a,c,d,e,f,g  

^a NEW ENGLAND CENTER FOR HEADACHE   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NEW YORK MEDICAL COLLEGE   (United States)

^d GLAXOSMITHKLINE   (United States)

^e MERCK RESEARCH LABORATORIES   (United States)

^f ASTRAZENECA   (United Kingdom)

^g Pharmacia ^*  (United States)

^h ABBOTT LABORATORIES   (United States)

ⁱ PFIZER

^j Forest Laboratories

^k BRISTOL MYERS SQUIBB   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ALMOTRIPTAN; ANTIMIGRAINE AGENT; ELETRIPTAN; FROVATRIPTAN; NARATRIPTAN; NEUROPEPTIDE; RIZATRIPTAN; SEROTONIN 1B AGONIST; SEROTONIN 1D AGONIST; SEROTONIN RECEPTOR; SUMATRIPTAN; ZOLMITRIPTAN;

ANTINOCICEPTION; DRUG EFFICACY; DRUG MECHANISM; DRUG TOLERABILITY; FATIGUE; HUMAN; MIGRAINE; NEUROTRANSMISSION; PARESTHESIA; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN SECRETION; REVIEW; TRIGEMINAL NERVE; VASOCONSTRICTION; VERTIGO;

CARBAZOLES; HUMANS; INDOLES; MIGRAINE DISORDERS; OXAZOLIDINONES; PIPERIDINES; PYRROLIDINES; RECEPTOR, SEROTONIN, 5-HT1B; RECEPTOR, SEROTONIN, 5-HT1D; RECEPTORS, SEROTONIN; SEROTONIN AGONISTS; SUMATRIPTAN; TRIAZOLES; TRYPTAMINES;

EID: 0036314986     PISSN: 00039942     EISSN: None     Source Type: Journal    
DOI: 10.1001/archneur.59.7.1084     Document Type: Review

References (50)

1. Current concepts of migraine pathophysiology
2. Neurogenic versus vascular mechanisms of sumatriptan and ergot alkaloids in migraine
3. Mechanisms and management of headache
4. Calcitonin gene-related peptide is present in mammalian cerebrovascular nerve fibres and dilates pial and peripheral arteries
5. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by substance P
6. Pathophysiology of migraine: New insights
7. Retinal plasma extravasation in animals but not in humans: Implications for the pathophysiology of migraine
8. The autonomic nervous system and the regulation of arterial tone in migraine
9. Nitric oxide is a key molecule in migraine and other vascular headaches
10. Serotonin in migraine: Theories, animal models and emerging therapies
11. Serotonin and migraine
12. The biology of serotonin receptors: Focus on migraine pathophysiology and treatment
13. Pharmacological aspects of experimental headache models in relation to acute antimigraine therapy
14. 1B/1D agonists inhibits trigeminal cell firing in the cat
15. Serotonin receptors and the acute attack of migraine
16. 1B receptor activation by sumatriotan and related agonists
17. Effects of sumatriptan on nitric oxide and superoxide balance during glyceryl trinitrate infusion in the rat: Implications for antimigraine mechanisms
18. 1B/1D receptor agonists abolish NMDA receptor-evoked enhancement of nitric oxide synthase activity and cGMP concentration in brain cortex slices
19. 1B-receptors
20. 1D-receptor agonists rizatriptan (MK-462) and sumatriptan in human isolated coronary artery: Outcome of two independent studies using different experimental protocols
21. Coronary side-effect potential of current and prospective antimigraine drugs
22. The novel antimigraine agent rizatriptan inhibits neurogenic dural vasodilation and extravasation
23. Regulation of calcitonin gene-related peptide secretion by a serotonergic antimigraine drug
24. 1B/1D agonist
25. 1B/1D receptor: A central action in migraine?
26. Rizatriptan has central antinociceptive effects against durally evoked responses
27. Axert tablets
28. Comparison of rizatriptan 10 mg vs naratriptan 2.4 mg in migraine
29. Current and emerging second-generation triptans in acute migraine therapy: A comparative review
30. Rizatriptan: A review of its efficacy in the management of migraine
31. Naratriptan: An alternative for migraine
32. Eletriptan in acute migraine: A doubleblind, placebo-controlled comparison to sumatriptan
33. Imitrex tablets
34. Naratriptan is effective and well tolerated in the acute treatment of migraine: Results of a double-blind, placebo-controlled, parallel-group study
35. A placebo-controlled crossover study of rizatriptan in the treatment of multiple migraine attacks
36. Naratriptan is effective and well tolerated in the acute treatment of migraine: Results of a double-blind, placebo-controlled, crossover study
37. Maxalt tablets
38. Sumatriptan: An updated review of its use in migraine
39. Efficacy and safety of sumatriptan tablets (25 mg, 50 mg, and 100 mg) in the acute treatment of migraine: Defining the optimum doses of oral sumatriptan
40. Zolmitriptan: A review of its use in migraine
41. Oral almotriptan vs oral sumatriptan in the abortive treatment of migraine
42. Zomig tablets
43. 1B/1D agonists
44. Antimigraine drugs
45. A longterm study to maximize migraine relief with Zomig
46. Oral therapy for migraine: Comparisons between rizatriptan and sumatriptan: A review of four randomized, double-blind clinical trials
47. Consistent efficacy and tolerability of almotriptan in the acute treatment of multiple migraine attacks: Results of a large, randomized, double-blind, placebo-controlled study
48. Frovatriptan: Widening therapeutic options in acute migraine
49. 1B/1D agonists in acute migraine with special reference to second generation agents