Low dose oral vitamin K to reverse acenocoumarol-induced coagulopathy: A randomized controlled trial

Thrombosis and Haemostasis

Volumn 88, Issue 1, 2002, Pages 48-51

  Ageno, Walter ^a   Crowther, M ^a   Steidl, L ^a   Ultori, C ^a   Mera, V ^a   Dentali, F ^a   Squizzato, A ^a   Marchesi, C ^a   Venco, A ^a  

^a OSPEDALE DI CIRCOLO   (Italy)

Author keywords

Acenocoumarol; Oral anticoagulants; Oral vitamin K

Indexed keywords

ACENOCOUMAROL; ANTICOAGULANT AGENT; PHYTOMENADIONE; VITAMIN K GROUP; ANTIFIBRINOLYTIC AGENT;

ACUTE HEART INFARCTION; ADULT; AGED; ARTICLE; BLOOD CLOTTING DISORDER; CLINICAL ARTICLE; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEEP VEIN THROMBOSIS; DOSE RESPONSE; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; DRUG WITHDRAWAL; FEMALE; FOLLOW UP; HEART ATRIUM FIBRILLATION; HUMAN; INTERNATIONAL STANDARD UNIT; MALE; PRIORITY JOURNAL; PROPHYLAXIS; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL; STROKE; CHEMICALLY INDUCED DISORDER; CHI SQUARE DISTRIBUTION; DRUG ANTAGONISM; INTERNATIONAL NORMALIZED RATIO; MIDDLE AGED; ORAL DRUG ADMINISTRATION;

ACENOCOUMAROL; ADMINISTRATION, ORAL; AGED; AGED, 80 AND OVER; ANTICOAGULANTS; ANTIFIBRINOLYTIC AGENTS; BLOOD COAGULATION DISORDERS; CHI-SQUARE DISTRIBUTION; DRUG ANTAGONISM; FEMALE; HUMANS; INTERNATIONAL NORMALIZED RATIO; MALE; MIDDLE AGED; VITAMIN K;

EID: 0036313760     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0037-1613152     Document Type: Article

References (17)

1. Oral anticoagulants: Mechanism of action, clinical effectiveness, and optimal therapeutic range
2. Bleeding complications of oral anticoagulant treatment: An inception-cohort, prospective collaborative study (ISCOAT)
3. Oral anticoagulation self-management and management by a specialist anticoagulation clinic: A randomised cross-over comparison
4. A randomized comparison of a computer-based dosing program with a manual system to monitor oral anticoagulant therapy
5. Prospective study of the outcomes of ambulatory patients with excessive warfarin anticoagulation
6. Conservative treatment of overanticoagulated patients
7. Effective reversal of warfarin-induced excessive anticoagulation with low dose vitamin K1
8. Reversal of excessive effect of regular anticoagulation: Low oral dose of phytonadione (vitamin K1) compared with warfarin discontinuation
9. Correction of excessive anticoagulation with low-dose oral vitamin K1
10. Comparing different routes and doses of phytonadione for reversing excessive anticoagulation
11. Intravenous versus subcutaneous vitamin K1 in reversing excessive oral anticoagulation
12. Time course of reversal of anticoagulant effect of warfarin by intravenous and subcutaneous phytonadione
13. Antagonism of warfarin-induced hypoprothrombinemia with use of low-dose subcutaneous vitamin K1
14. Low-dose oral vitamin K reliably reverses over-anticoagulation due to warfarin
15. Treatment of warfarin-associated coagulopathy with oral vitamin K. A randomised controlled trial
16. Warfarin metabolism and drug-drug interaction