Influence of ACE inhibition on myocardial damage, the kallikrein-kinin system and hemostasis during cardiopulmonary bypass surgery

Thoracic and Cardiovascular Surgeon

Volumn 50, Issue 3, 2002, Pages 150-154

  Walter, Thomas ^a   Helber, U ^a   Bail, D ^b   Heller, W ^a   Hoffmeister, H M ^a  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

ACE inhibitor; Cardiopulmonary bypass grafting; Hemostasis; Kallikrein kinin system; Troponin T

Indexed keywords

APROTININ; CREATINE KINASE; CREATINE KINASE MB; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENALAPRIL; ENALAPRIL MALEATE; FIBRINOGEN; KALLIKREIN; LACTATE DEHYDROGENASE; PLACEBO; THROMBIN ANTITHROMBIN COMPLEX; TROPONIN T;

ADULT; AGED; ARTICLE; CARDIOPULMONARY BYPASS; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORONARY ARTERY BYPASS SURGERY; CORONARY ARTERY DISEASE; DRUG EFFICACY; FEMALE; HEART MUSCLE ISCHEMIA; HEMOSTASIS; HUMAN; KALLIKREIN KININ SYSTEM; MALE; PEROPERATIVE COMPLICATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

ADMINISTRATION, ORAL; ADULT; AGED; AGED, 80 AND OVER; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CORONARY ARTERY BYPASS; CORONARY DISEASE; DOUBLE-BLIND METHOD; ENALAPRIL; FEMALE; FIBRINOGEN; HEART; HEMOSTASIS; HUMANS; INTRAOPERATIVE COMPLICATIONS; KALLIKREIN-KININ SYSTEM; MALE; MIDDLE AGED; MYOCARDIAL REPERFUSION INJURY;

EID: 0036313241     PISSN: 01716425     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2002-32409     Document Type: Article

References (22)

1. Does bradykinin play a role in the cardiac antiischemic effect of the ACE-inhibitors?
2. Non-invasive assessment of perioperative myocardial cell damage by circulating cardiac troponin T
3. Cardiac troponin I plasma levels for diagnosis and quantitation of perioperative myocardial damage in patients undergoing coronary artery bypass surgery
4. Lower cardiac troponin T levels in patients undergoing cardiopulmonary bypass and receiving high-dose aprotinin therapy indicate reduction of perioperative myocardial damage
5. One month follow-up of haemostatic variables in patients undergoing aortocoronary bypass surgery. Effect of aprotinin
6. Alterations in fibrinolysis and coagulation associated with cardiopulmonary bypass
7. Angiotensin-converting enzyme inhibitors downregulate tissue factor synthesis in monocytes
8. ACE inhibitor quinapril reduces the arterial expression of NF-kappaB-dependent promflammatory factors but not of collagen I in a rabbit model of atherosclerosis
9. Measurement of myosin light chain I and troponin T as markers of myocardial damage after cardiac surgery
10. Troponin I, troponin T, or creatine kinase-MB to detect perioperative myocardial damage after coronary artery bypass surgery
11. Myonecrosis after revascularization procedures, J
12. Creatine kinase MB isoforms: Sensitive markers of ischemic myocardial damage
13. Changes in serum CK-MB mass after coronary artery bypass surgery
14. Influence of local converting enzyme inhibition on angiotensin and bradykinin effects in ischemic rat hearts
15. Can clonidine, enoximone, and enalaprilat help to protect the myocardium against ischaemia in cardiac surgery?
16. Aprotinin. A review of its pharmacology and therapeutic efficacy in reducing blood loss associated with cardiac surgery
17. Changes in the coagulation and fibrinolytic systems during and after cardiopulmonary bypass surgery
18. The kallikrein-kinin system in myocardial ischemia and myocardial infarct. Experimental studies
19. Late changes in hemostatic parameters following open-heart surgery
20. The role of the protein C-thrombomodulin system and fibrinolysis during cardiovascular surgery: Influence of acute preoperative plasmapheresis
21. Seipel L Alterations of coagulation and fibrinolytic and kallikrein-kinin systems in the acute and postacute phases in patients with unstable angina pectoris
22. Alterations of the kallikrein system in patients with acute myocardial syndromes in comparison with patients with stable angina pectoris