The effect of FasL expression on pancreatic islet allografts

Chinese Medical Journal

Volumn 115, Issue 7, 2002, Pages 1006-1009

  Zhan, Wenhua ^a   Cai, Shirong ^a   Wang, Jianping ^a   He, Yulong ^a   Zheng, Zhangqing ^a   Peng, Junsheng ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Fas ligand; Gene therapy; Immune privilege; Islet transplantation

Indexed keywords

FAS LIGAND; GLUCOSE; STREPTOZOCIN;

ADENOVIRUS; ALLOGRAFT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; CELL COUNT; CELL TRANSPLANTATION; CONTROLLED STUDY; FOLLOW UP; GENE TRANSFER; GENETIC TRANSFECTION; GLUCOSE BLOOD LEVEL; GRAFT REJECTION; GRAFT SURVIVAL; IMMUNE RESPONSE; LYMPHOCYTE ACTIVATION; LYMPHOCYTIC INFILTRATION; MALE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PANCREAS FUNCTION; PANCREAS ISLET; PANCREAS ISLET CELL; PANCREAS ISLET TRANSPLANTATION; PROTEIN EXPRESSION; RAT; RECIPIENT; SERTOLI CELL; STREPTOZOCIN DIABETES; TESTIS CELL; VIRUS INFECTION;

ANIMALS; APOPTOSIS; FAS LIGAND PROTEIN; IMMUNOHISTOCHEMISTRY; ISLETS OF LANGERHANS TRANSPLANTATION; MALE; MEMBRANE GLYCOPROTEINS; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSFECTION; TRANSPLANTATION, HOMOLOGOUS;

EID: 0036312580     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Apoptosis, graft rejection, and transplantation tolerance
2. A role for CD95 ligand in preventing graft rejection
3. Role of Fas-Fas ligand interactions in the immunorejection of allogeneic mouse corneal transplants
4. Cotransplantation of allogeneic islets with allogeneic testicular cell aggregates allows long-term graft survival without systemic immunosuppression
5. Prevention of islet allograft rejection with engineered myoblasts expressing FasL in mice
6. Transgenic expression of CD95 ligand on islet beta cells induces a granulocytic infiltration but does not confer immune privilege upon islet allografts
7. Fas ligand gene transfer to renal allografts in rats: Effects on allograft survival
8. Prolonged survival of rat liver allografts transfected with Fas ligand-expressing plasmid
9. Accelerated rejection of FAS ligand-expressing heart grafts