The catalytic mechanism of indole-3-glycerol phosphate synthase: Crystal structures of complexes of the enzyme from Sulfolobus solfataricus with substrate analogue, substrate, and product

Journal of Molecular Biology

Volumn 319, Issue 3, 2002, Pages 757-766

  Hennig, M ^a   Darimont, B D ^a   Jansonius, J N ^a   Kirschner, K ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

Author keywords

( )8 barrel; Catalytic mechanism; Ligand complexes; Tryptophan biosynthesis; X ray structural analysis

Indexed keywords

1 (2 CARBOXYPHENYLAMINO) 1 DEOXYRIBULOSE 5 PHOSPHATE; ANTHRANILIC ACID; CARBON; CARBOXYLIC ACID; GLUTAMIC ACID; INDOLE 3 GLYCEROL PHOSPHATE SYNTHASE; LYSINE; PHENOL DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; HYDROPHOBICITY; NONHUMAN; PRIORITY JOURNAL; SULFOLOBUS SOLFATARICUS; X RAY CRYSTALLOGRAPHY;

SULFOLOBUS; SULFOLOBUS SOLFATARICUS;

EID: 0036308014     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2836(02)00378-9     Document Type: Article

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