Effect of myocardial stunning on thiol status, myofibrillar ATPase and troponin I proteolysis

Molecular and Cellular Biochemistry

Volumn 233, Issue 1-2, 2002, Pages 145-152

  Kaplán, Peter ^a   Matejovicová, Milena ^a   Lehotský, Ján ^a   Flameng, Willem ^a  

^a University Teaching Hospital in Martin   (Slovakia)

Author keywords

Mg2+ ATPase; Myocardial stunning; Myofilament; Thiols; Troponin I

Indexed keywords

ADENOSINE TRIPHOSPHATASE; CALCIUM ION; HEART MUSCLE EXTRACT; MAGNESIUM ION; MUSCLE PROTEIN; THIOL GROUP; TROPONIN I;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY TEMPERATURE; CONTROLLED STUDY; ENZYME ACTIVITY; HEART CONTRACTION; HEART LEFT VENTRICLE; HEART MUSCLE CONTRACTILITY; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; IMMUNOREACTIVITY; ISOLATED HEART; MUSCLE FIBRIL; MUSCLE FUNCTION; NONHUMAN; OXIDATION; PROTEIN ANALYSIS; PROTEIN DEGRADATION; RABBIT; STUNNED HEART MUSCLE; WESTERN BLOTTING;

ADENOSINE TRIPHOSPHATE; ANIMALS; CA(2+) MG(2+)-ATPASE; CALCIUM; CYSTEINE ENDOPEPTIDASES; MULTIENZYME COMPLEXES; MYOCARDIAL CONTRACTION; MYOCARDIAL REPERFUSION INJURY; MYOCARDIAL STUNNING; MYOFIBRILS; PROTEASOME ENDOPEPTIDASE COMPLEX; RABBITS; SULFHYDRYL COMPOUNDS; TROPONIN I;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 0036307264     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1015514614183     Document Type: Article

References (45)

1. 2+ activation of contraction as a consequence of reperfusion-induced cellular calcium overload in ferret hearts
2. Decreased myofilament responsiveness in myocardial stunning follows transient calcium overload during ischemia and reperfusion
3. Altered calcium sensitivity of isometric tension in myocyte-sized preparations of porcine post ischemic stunned myocardium
4. 2+ responsiveness and altered diastolic function in intact ventricular muscle
5. 2+-dependent proteolysis?
6. 2+ of myofibrils isolated from stunned and non-stunned porcine myocardium
7. Role of troponin I proteolysis in the pathogenesis of stunned myocardium
8. Breakdown and release of myofilament proteins during ischemia and ischemia/reperfusion in rat hearts. Identification of degradation products and effects on the pCa-force relation
9. Troponin I degradation and covalet complex formation accompanies myocardial ischemia/reperfusion injury
10. The effects of levosimendan on the left ventricular function and protein phosphorylation in post-ischemic guinea pig hearts
11. Cardiomyocyte troponin T immunoreactivity is modified by cross-linking resulting from intracellular calcium overload
12. Molecular and cellular mechanisms of myocardial stunning
13. In search of the proteins that cause myocardial stunning
14. Phosphorylation by protein kinases A and C of myofibrillar proteins in rabbit stunned and non-stunned myocardium
15. Binding of cytosolic proteins to myofibrils in ischemic rat hearts
16. Expression of calcium regulatory proteins in short-term hibernation and stunning in the in situ porcine heart
17. Absence of troponin I degradation or altered sarcoplasmic reticulum uptake protein expression after reversible ischemia in swine
18. Enhancement of recovery of myocardial function by oxygen free-radical scavengers after reversible regional ischemia
19. Beneficial actions of superoxide dismutase and catalase in stunned myocardium of dogs
20. Superoxide dismutase plus catalase improve contractile function in the canine model of the 'stunned' myocardium
21. Direct measurement of free radical generation following reperfusion of ischemic myocardium
22. The role of oxidative stress in the genesis of the heart disease
23. Evidence for the role of oxidative stress in acute ischemic heart disease: A brief review
24. Oxidative stress and cardiac disease
25. Selective effects of oxygen free radicals on excitation-contraction coupling in ventricular muscle. Implications for the mechanism of stunned myocardium
26. Distinct roles of peroxynitrite and hydroxyl radical in triggering stunned myocardium-like impairment of cardiac myocytes in vitro
27. Alterations in cardiac contractile proteins due to oxygen free radicals
28. Attenuation of myocardial reperfusion injury by sulfhydryl-containing angiotensin converting enzyme inhibitors
29. Protective effect of captopril on ischemic myocardium
30. Myocardial sulfhydryl pool alterations occur during reperfusion after brief and prolonged myocardial ischemia in vivo
31. Effect of pyruvate on rat heart thiol status during ischemia and hypoxia followed by reperfusion
32. New insights on myocardial pyridine nucleotides and thiol redox state in ischemia and reperfusion damage
33. Effect of ischemia and reperfusion on sarcoplasmic reticulum calcium uptake
34. Inotropic responses to isoproterenol and phosphodiesterase inhibitors in intact guinea pig hearts: Comparison of cyclic AMP levels and phosphorylation of sarcoplasmic reticulum and myofibrillar proteins
35. Rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein dye binding
36. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
37. Spectrophotometric assay of thiols
38. An improved assay for nanomole amounts of inorganic phosphate
39. Preload induces troponin I degradation independently of myocardial ischemia
40. 2+ handling
41. Specific degradation of troponin T and I by μ-calpain and its modulation by substrate phosphorylation
42. Modification of contractile proteins by oxygen free radicals in rat heart
43. Actin is oxidized during myocardial ischemia
44. 2+-sensitive myofibrillar ATPase activity and creatine kinase kinetics
45. Alterations in myofibrillar function and protein profiles after complete global ischemia in rat hearts