The activation energy for insertion of transmembrane α-helices is dependent on membrane composition

Journal of Molecular Biology

Volumn 319, Issue 3, 2002, Pages 839-853

  Meijberg, Wim ^a   Booth, Paula J ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Activation energy; Kinetics; Lateral pressure; Membrane protein folding; Transmembrane helix insertion

Indexed keywords

1,2 DIOLEOYL ALPHA PHOSPHATIDYLCHOLINE; 1,2 DIOLEOYL ALPHA PHOSPHATIDYLETHANOLAMINE; CHOLINE DERIVATIVE; ETHANOLAMINE DERIVATIVE; LYSINE; PEPTIDE DERIVATIVE; UNCLASSIFIED DRUG;

ALPHA HELIX; ARTICLE; KINETICS; LIPID BILAYER; PH; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FOLDING; TEMPERATURE DEPENDENCE;

INSERTION SEQUENCES;

EID: 0036306814     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2836(02)00342-X     Document Type: Article

References (44)

1. Modulation of CTP: Phosphocholine cytidylyltransferase by membrane curvature elastic stress
2. 2+-ATPase of sarcoplasmic reticulum
3. Lipid headgroup and acyl chain composition modulate the MI-MII equilibrium of rhodopsin in recombinant membranes
4. Probability of alamethicin conductance states varies with nonlamellar tendency of bilayer phospholipids
5. Amphiphilic mesophases made of defects
6. Swollen lyotropic cubic phases in fully hydrated mixtures of monoolein, phosphatidylcholine and phosphatidylethanolamine
7. Sensing isothermal changes in the lateral pressure in model membranes using di-pyrenyl phosphatidylcholine
8. Intrinsic curvature hypothesis for biomembrane lipid composition: A role for non-bilayer lipids
9. Manipulating the folding of membrane proteins: Using the bilayer to our advantage
10. Evidence that bilayer bending rigidity affects membrane protein folding
11. Molecular theory for amphiphite packing and elastic properties of monolayers and bilayers
12. Slow alpha helix formation during folding of a membrane protein
13. Modulation of folding and assembly of the membrane protein bacteriorhodopsin by intermolecular forces within the lipid bilayer
14. Anionic phospholipids modulate peptide insertion into membranes
15. Threshold hydrophobicity dictates helical conformations of peptides in membrane environments
16. Guidelines for membrane protein engineering derived from de novo designed model peptides
17. Distribution analysis of depth-dependent fluorescence quenching in membranes: A practical guide
18. Analysis of protein and peptide penetration into membranes by depth-dependent fluorescence quenching: Theoretical considerations
19. Fluorescence study of a mutant cytochrome b5 with a single tryptophan in the membrane-binding domain
20. Spontaneous, pH-dependent membrane insertion of a transbilayer alpha-helix
21. Structure of a fluid dioleoylphosphatidylcholine bilayer determined by joint refinement of X-ray and neutron diffraction data. III. Complete structure
22. Control of the transmembrane orientation and interhelical interactions within membranes by hydrophobic helix length
23. Transmembrane orientation of hydrophobic alpha-helices is regulated both by the relationship of helix length to bilayer thickness and by the cholesterol concentration
24. Estimations of lipid bilayer geometry in fluid lamellar phases
25. Cooperative membrane insertion of magainin correlated with its cytolytic activity
26. X-ray diffraction study of lipid bilayer membranes interacting with amphiphilic helical peptides: Diphytanoyl phosphatidylcholine with alamethicin at low concentrations
27. Kinetic study of folding and misfolding of diacylglycerol kinase in model membranes
28. The thermal stability and domain interactions of the mannitol permease of Escherichia coli. A differential scanning calorimetry study
29. Kinetic-study into the irreversible thermal-denaturation of bacteriorhodopsin
30. Designing transmembrane alpha-helices that insert spontaneously
31. Towards membrane protein design: pH-sensitive topology of histidine-containing polypeptides
32. Semisynthetic proteins: Model systems for the study of the insertion of hydrophobic peptides into preformed lipid bilayers
33. Thermodynamics of the membrane insertion process of the M13 procoat protein, a lipid bilayer traversing protein containing a leader sequence
34. Membrane protein folding and stability: Physical principles
35. Structure of the inverted hexagonal (HII) phase, and non-lamellar phase transitions of lipids
36. Membrane curvature, lipid segregation, and structural transitions for phospholipids under dual-solvent stress
37. Ionization and ion binding
38. 31P NMR study
39. Destabilization of phosphatidylethanolamine liposomes at the hexagonal phase transition temperature
40. How to measure and predict the molar absorption coefficient of a protein
41. The effect of surface charge on the hydrolysis kinetics of partially hydrogenated egg phosphatidylcholine and egg phosphatidylglycerol in aqueous liposome dispersions
42. Chemical hydrolysis of DOTAP and DOPE in a liposomal environment
43. Circular dichroism analyses of membrane proteins: An examination of differential light scattering and absorption flattening effects in large membrane vesicles and membrane sheets
44. Determination of the helix and beta form of proteins in aqueous solution by circular dichroism