The role of stoichiometric analysis in studies of metabolism: An example

Journal of Theoretical Biology

Volumn 216, Issue 2, 2002, Pages 179-191

  Cornish Bowden, Athel ^a   Hofmeyr, Jan Hendrik S ^b  

^a CNRS   (France)

^b STELLENBOSCH UNIVERSITY   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE NUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE;

METABOLISM; STOICHIOMETRY;

ANALYTIC METHOD; ARTICLE; CONCENTRATION (PARAMETERS); GLYCOLYSIS; METABOLISM; METABOLITE; NONHUMAN; NORMAL DISTRIBUTION; PHOSPHORYLATION; PRIORITY JOURNAL; STOICHIOMETRY; TRYPANOSOMA BRUCEI;

TRYPANOSOMA; TRYPANOSOMA BRUCEI;

EID: 0036304317     PISSN: 00225193     EISSN: None     Source Type: Journal    
DOI: 10.1006/jtbi.2002.2547     Document Type: Article

References (36)

1. Cross-linking of the enzymes in the glycosome of Trypanosoma brucei
2. Glycolysis in bloodstream form Trypanosoma brucei can be understood in terms of the kinetics of the glycolytic enzymes
3. What controls glycolysis in bloodstream form Trypanosoma brucei?
4. Compartmentation protects trypanosomes from the dangerous design of glycolysis
5. Using metabolic control analysis to improve the selectivity and effectiveness of drugs against parasitic diseases
6. Kinetics of inhibition of 5-enolpyruvylshikimate-3-phosphate synthase by glyphosate
7. Why is uncompetitive inhibition so rare?
8. From genome to cellular phenotype - A role for metabolic flux analysis?
9. Information transfer in metabolic pathways: Effects of irreversible steps in computer models
10. Computer simulation as a tool for studying metabolism and drug design
11. MetaModel: A program for modelling and control analysis of metabolic pathways on the IBM PC and compatibles
12. Strategies for manipulating metabolic fluxes in biotechnology
13. Prospects for antiparasitic drugs: The case of Trypanosoma brucei, the causative agent of African sleeping sickness
14. Book review
15. Quantitative assessment of regulation in metabolic systems
16. Regulating the cellular economy of supply and demand
17. The control of flux
18. Regulation and redirection of metabolism: Incorporating regulatory information in flux calculation
19. Gepasi: A software package for modelling the dynamics, steady states and control of biochemical and other systems
20. Biochemistry by numbers: Simulation of biochemical pathways with Gepasi 3
21. Metabolic aspects of glycosomes in Trypanosomatidae - New data and views
22. Glycolytic enzymes of Trypanosoma brucei: Simultaneous purification, intraglycosomal concentrations and physical properties
23. Compartmentation of carbohydrate metabolism in trypanosomes
24. Metabolic control theory: A structural approach
25. Analysis of sucrose accumulation in the sugarcane culm on the basis of in vitro kinetic data
26. An integrated approach to the analysis of the control and regulation of cellular systems
27. Scamp, a general-purpose simulator and metabolic control analysis program
28. Jarnac: A system for interactive metabolic analysis
29. What information about the conserved-moiety structure of chemical reaction systems can be derived from their stoichiometry?
30. Determining all extreme semi-positive conservation relations in chemical reaction systems: A test criterion for conservativity
31. Detecting strictly detailed balanced sub-networks in open chemical reaction networks
32. A general definition of metabolic pathways useful for systematic organization and analysis of complex metabolic networks
33. The inhibition of pyruvate transport across the plasma membrane of the bloodstream form of Trypanosoma brucei and its metabolic implications