Phototoxicity studies of pazufloxacin mesilate, a novel parenteral quinolone antimicrobial agent - In vitro and in vivo studies

Japanese Journal of Antibiotics

Volumn 55, Issue 3, 2002, Pages 259-269

  Nagasawa, Mineko ^a   Nakamura, Shozo ^a   Miyazaki, Miyono ^a   Nojima, Yasuyuki ^a   Hayakawa, Hiroyoshi ^a   Kawamura, Yasuhito ^a  

^a TOYAMA CHEMICAL CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CIPROFLOXACIN; ENOXACIN; LOMEFLOXACIN; NALIDIXIC ACID; OFLOXACIN; PAZUFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SPARFLOXACIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; DOSE RESPONSE; DRUG POTENCY; DRUG STABILITY; DRUG STRUCTURE; GUINEA PIG; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PHOTOALLERGY; PHOTOTOXICITY; RAT; ULTRAVIOLET A RADIATION;

ANIMALS; ANTI-INFECTIVE AGENTS; CELLS, CULTURED; CIPROFLOXACIN; DERMATITIS, PHOTOTOXIC; ENOXACIN; FEMALE; FLUOROQUINOLONES; GUINEA PIGS; NALIDIXIC ACID; OFLOXACIN; OXAZINES; QUINOLONES; RATS; RATS, SPRAGUE-DAWLEY; ULTRAVIOLET RAYS;

EID: 0036303110     PISSN: 03682781     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

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6. Mechanistic studies of the phototoxic potential of PD 117596, a quinolone antibacterial compound
7. Important role of oxygen metabolites in quinolone antibacterial agent-induced cutaneous phototoxicity in mice
8. Possible direct role of reactive oxygens in the cause of cutaneous phototoxicity induced by five quinolones in mice