Cleavage of Treponema denticola PrcA polypeptide to yield protease complex-associated proteins Prca1 and Prca2 is dependent on PrtP

Journal of Bacteriology

Volumn 184, Issue 14, 2002, Pages 3864-3870

  Lee, Si Young ^a   Bian, Xue Lin ^a   Wong, Grace W K ^a   Hannam, Pauline M ^a   McBride, Barry C ^a   Fenno, J Christopher ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; CHYMOTRYPSIN LIKE PROTEASE; MEMBRANE PROTEIN; MUTANT PROTEIN; POLYPEPTIDE; PROTEIN PRCA; PROTEIN PRCA1; PROTEIN PRCA2; PROTEIN PRTP; PROTEINASE; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

ACYLATION; AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIUM MUTANT; CELL INVASION; CONTROLLED STUDY; DNA SEQUENCE; ENZYME ACTIVITY; IMMUNOBLOTTING; NONHUMAN; NUCLEOTIDE SEQUENCE; OLIGOMERIZATION; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEIN STABILITY; SEQUENCE HOMOLOGY; TREPONEMA DENTICOLA;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; CHYMOTRYPSIN; ESCHERICHIA COLI; MOLECULAR SEQUENCE DATA; SUBTILISINS; TREPONEMA;

BACTERIA (MICROORGANISMS); TREPONEMA; TREPONEMA DENTICOLA;

EID: 0036302650     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.184.14.3864-3870.2002     Document Type: Article

References (30)

1. Basic local alignment search tool
2. An inexpensive solid medium for obtaining colony-forming units of oral spirochetes
3. Insertional inactivation of the prtP gene of Treponema denticola confirms dentilisin's disruption of epithelial junctions
4. Degradation of endogenous plasma membrane fibronectin concomitant with Treponema denticola 35405 adhesion to gingival fibroblasts
5. Cytopathic effects of the major surface protein (Msp) and the chymotrypsinlike protease (CTLP) of Treponema denticola
6. The opdB locus encodes the trypsin-like peptidase activity of Treponema denticola
7. Virulence factors of oral treponemes
8. Sequence analysis, expression and binding activity of recombinant major outer sheath protein (Msp) of Treponema denticola
9. Mutagenesis of outer membrane virulence determinants of the oral spirochete Treponema denticola
10. Virulence of a Porphyromonas gingivalis W83 mutant defective in the prtH gene
11. GeneFisher-software support for the detection of postulated genes
12. Degradation of host protease inhibitors and activation of plasminogen by proteolytic enzymes from Porphyromonas gingivalis and Treponema denticola
13. Cellular location of a Treponema denticola chymotrypsinlike protease and importance of the protease in migration through the basement membrane
14. Spirochaetal lipoproteins and pathogenesis
15. Sulfhydryl-dependent attachment of Treponema denticola to laminin and other proteins
16. Proteolytic activity among various oral Treponema species and cloning of a prtP-like gene of Treponema socranskii subsp. socranskii(1)
17. Dentilisin activity affects the organization of the outer sheath of Treponema denticola
18. Characterization of the Treponema denticola prtP gene encoding a prolyl-phenylalanine-specific protease (dentilisin)
19. The proteolytic systems of lactic acid bacteria
20. Gene inactivation in the oral spirochete Treponema denticola: Construction of an flgE mutant
21. Role of the chymotrypsin-like membrane-associated proteinase from Treponema denticola ATCC 35405 in inactivation of bioactive peptides
22. Expert system for predicting protein localization sites in gram-negative bacteria
23. Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites
24. First evidence for gene replacement in Leptospira spp. Inactivation of L. biflexa flab results in non-motile mutants deficient in endoflagella
25. Isolation of a chymotrypsinlike enzyme from Treponema denticola
26. Cytopathic effects of Treponema denticola chymotrypsin-like proteinase on migrating and stratified epithelial cells
27. A maturation protein is essential for production of active forms of Lactococcus lactis SK11 serine proteinase located in or secreted from the cell envelope
28. Improved M13 phage cloning vectors and host strains: Nucleotide sequences of the M13mp18 and pUC19 vectors