Diethylanilineborane: A practical, safe, and consistent-quality borane source for the large-scale enantioselective reduction of a ketone intermediate in the synthesis of (R,R)-formoterol

Organic Process Research and Development

Volumn 6, Issue 2, 2002, Pages 146-148

  Wilkinson, H Scott ^a   Tanoury, Gerald J ^a,b   Wald, Stephen A ^a   Senanayake, Chris H ^a  

^a SUNOVION PHARMACEUTICALS INC   (United States)

^b VERTEX PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BORANE DERIVATIVE; DIETHYLANILINEBORANE; FORMOTEROL; KETONE; TARTARIC ACID; UNCLASSIFIED DRUG;

ARTICLE; DRUG SYNTHESIS; ENANTIOSELECTIVITY; REDUCTION; SAFETY;

EID: 0036301714     PISSN: 10836160     EISSN: None     Source Type: Journal    
DOI: 10.1021/op015504b     Document Type: Article

References (23)