Aerosol orgotein (Ontosein®) for the prevention of radiotherapy-induced adverse effects in head and neck cancer patients: A feasibility study

Neoplasma

Volumn 49, Issue 3, 2002, Pages 201-208

  Escribano, A ^a   Garcia Grande A ^a   Montanes P ^a   Miralles, L ^a   Garcia A ^a  

^a HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

Author keywords

Cancer; Head and neck cancer; Orgotein; Radiation therapy; Radiation induced adverse effects

Indexed keywords

COBALT 60; SUPEROXIDE DISMUTASE;

ADULT; AEROSOL; AGED; ARTICLE; CANCER RADIOTHERAPY; CANCER STAGING; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE SEVERITY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG INDUCED DISEASE; DRUG SAFETY; DYSPHAGIA; FEMALE; GLOTTIS; HEAD CANCER; HUMAN; LARYNX EDEMA; MALE; MUCOSA INFLAMMATION; NEBULIZER; NECK CANCER; PROPHYLAXIS; RADIATION HAZARD; RADIATION SICKNESS; SKIN MANIFESTATION; TREATMENT OUTCOME; XEROSTOMIA;

EID: 0036300161     PISSN: 00282685     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. La radiofibrose est réversible
2. The pathogenic role of superoxide radicals in inflammation: Efficacy of exogenous superoxide dismutase
3. Effects of superoxide dismutase topical treatment on human skin radiofibrosis. A pathological study
4. Superoxide dismutase, an enzymic function for erythrocuprein hemocuprein
5. Superoxide dismutase inhibits radiation induced lung injury in hamsters
6. Selective cytoprotection by amifostine in simultaneous radiochemotherapy of head and neck cancer
7. Protection of normal tissues from the cytotoxic effects of chemotherapy by amifostine (ethyol): Clinical experiences
8. Successful treatment of radiation-induced fibrosis using liposomal Cu/Zn superoxide dismutase: Clinical trial
9. Orgotein efficacy in ameliorating side effects due to radiation therapy: I. Doubleblind placebo-controlled trial in patients with bladder tumors
10. Orgotein efficacy in ameliorating side-effects due to radiation therapy
11. Treatment of autoimmune diseases with superoxide dismutase and D-penicillamine
12. Effect of GM-CSF in the radiation induced mucositis
13. Superoxide dismutase
14. Alternating chemotherapy (CT) + radiotherapy (RT) with amifostine (A) protection for head and neck cancer (HN): Early stop of a randomised trial
15. Consideraciones generales: Aspectos radiobiológicos y físicos
16. Efficacy and safety of granulocyte macrophage-colony stimulating factor (GM-CSF) on the frequency and severity of radiation mucositis in patients with head and neck carcinoma
17. Final report on phase I trial of WR-2721 before protracted fractionated radiation therapy
18. Does sucralfate reduce the acute side-effects in head and neck cancer treated with radiation therapy? A double-blind randomized trial
19. Sucralfate mouth washing in the prevention of radiation-induced mucositis: A placebo-controlled double-blind randomized study
20. Copper and zinc containing superoxide dismutase, manganese containing SOD, catalase and glutathione peroxidase in normal and neoplastic human cell lines and normal human tissues
21. Orgotein: A new drug for the treatment of radiation cystitis
22. Orgotein: A new drug for the treatment of radiation cystitis
23. The biology and pathology of oxygen radicals
24. Superoxide and inflammation: A mechanism for the anti-inflammatory activity of super-oxide dismutase
25. Preliminary results of a pilot study using WR-2721 before fractionated irridiation of the head and neck to reduce salivary gland dysfunction
26. Orgotein (superoxide dismutase): A drug for the amelioration of radiation-induced side effects. A double-blind placebo-controlled study in patients with bladder tumours
27. Aspects médicaux des superoxide dismutases
28. Orgotein in radiation treatment of bladder. A report on allergic reactions and lack of radioprotective effect
29. Orgoteína: Acción terapéutica sobre la toxicidad crónica producida por la radioterapia de los tumores de cabeza y cuello
30. Evaluation del l'effet therapeutique de la superoxide dismutase dans la fibrose radio-induit apres traitment pour cancer du sein
31. A randomized double blind placebo controlled multicenter study of mesalazine for the prevention of acute radiation enteritis
32. Granulocyte macrophage colony stimulating factor mouthwashes heal oral ulcers during head and neck radiation therapy
33. Eficacia de la orgoteína en el tratamiento de la fibrosis y xerostomía radioinducidas
34. Prevention with orgotein of radioinduce effects in patients with head and neck tumours
35. Comparison of intra-articular use of superoxide dismutase with a corticoid in the treatment of degenerative and inflammatory alteration of the finger joints
36. Influye el uso de orgoteína en el control tumoral?
37. Efficacy of sucralfate in the prophylaxis of diarrhea secondary to acute radiation-induced enteritis. Preliminary results of a double blind randomized trial
38. Local control of carcinoma of the tonsil by radiation therapy: An analysis of patterns of of fractionation in nine institutions