Several approaches to prepare matrice containing soluble drug with zero-order release kinetics

Chinese Pharmaceutical Journal

Volumn 37, Issue 3, 2002, Pages 192-195

  Lin, Xiao ^a   Chen, Ji Min ^a  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

CMC Na; Combined matrix; HPMC; Hydromorphone hydrochloride; Octadecanol

Indexed keywords

DIFFUSION; DISSOLUTION; GRANULATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROPHOBICITY;

SOLUBLE DRUGS;

DRUG PRODUCTS;

CARBOXYMETHYLCELLULOSE; DRUG; HYDROMORPHONE; OCTADECANOL;

ARTICLE; DRUG DIFFUSION; DRUG FORMULATION; DRUG GRANULATION; DRUG RELEASE; DRUG SOLUBILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROPHOBICITY; KINETICS;

EID: 0036297821     PISSN: 10012494     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Formulation and characterization of new layered diffusional matrices for zero-order sustained release
2. Multi-layered hydrophilic matrices as constant release devices
3. Multilayer tablets as drug delivery devices
4. Drug release modulation by physical restrictions of matrix swelling
5. Sustained release tablet formulation of diethylcarbomazine
6. Compressed donut-shaped tablets with zero-order release kinetics
7. A new gradient matrix: Formulation and characterization
8. Design and manufacture of a zero-order sustained-release pellet dosage form through nonuniform drug distribution in a diffusional matrix