Impaired regeneration of dystrophin-deficient muscle fibers is caused by exhaustion of myogenic cells

Brazilian Journal of Medical and Biological Research

Volumn 35, Issue 6, 2002, Pages 691-695

  Luz, M A M ^a   Marques, M J ^a   Santo Neto, H ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Bupivacaine; Duchenne muscular dystrophy; mdx fiber regeneration; Muscle degeneration

Indexed keywords

BUPIVACAINE; DYSTROPHIN;

ADOPTIVE IMMUNOTHERAPY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DUCHENNE MUSCULAR DYSTROPHY; EXHAUSTION; GENE THERAPY; MALE; MOUSE; MUSCLE ATROPHY; MUSCLE CELL; MUSCLE REGENERATION; MYOFIBROSIS; NONHUMAN; SATELLITE CELL; TIBIALIS ANTERIOR MUSCLE;

ANIMALIA;

EID: 0036295263     PISSN: 0100879X     EISSN: 1414431X     Source Type: Journal    
DOI: 10.1590/S0100-879X2002000600009     Document Type: Article

References (20)

1. The complete sequence of dystrophin predicts a rod-shaped cytoskeletal protein
2. Muscular dystrophies
3. X-chromosome linked muscular dystrophy (mdx) in the mouse
4. Phenotype of dystrophinopathy in old mdx mice
5. mdx mice show progressive weakness and muscle deterioration with age
6. Evidence for a myogenic stem cell that is exhausted in dystrophic muscle
7. Impaired functional and structural recovery after muscle injury in dystrophic mdx mice
8. Aging normal and dystrophic mouse muscle: Analysis of myogenicity in cultures of living single fibers
9. Regenerative capacity of mdx mouse muscles after repeated applications of myo-necrotic bupivacaine
10. Acetylcholine receptors and neuronal nitric oxide synthase distribution at the neuromuscular junction of regenerated muscle fibers
11. Muscle precursor cells injected into irradiated mdx mouse persist after serial injury
12. Muscle regeneration after imposed injury is better in younger than older mdx dystrophic mice
13. Chronic myopathy induced by repeated bupivacaine injections
14. The satellite cell and muscle regeneration
15. Immunobiology and the future of myoblast transfer therapy
16. Adeno-associated virus vector carrying human minidystrophin genes effectively ameliorates muscular dystrophy in mdx mouse model
17. Antisense-induced exon skipping and synthesis of dystrophin in the mdx mouse
18. Combined immunosuppression of mycophenolate mofetil and FK506 for myoblast transplantation in mdx mice
19. Prior culture with concanavalin A increases intramuscular migration of transplanted myoblast
20. Dystrophin expression in the mdx mouse restored by stem cell transplantation