A circular RNA-DNA enzyme obtained by in vitro selection

Biochemical and Biophysical Research Communications

Volumn 292, Issue 4, 2002, Pages 1111-1115

  Kong, Xiang duo ^a   Zhu, Shi zhen ^a   Gou, Xiao jun ^a   Wang, Xiao ping ^a   Zhang, Hong ying ^a   Zhang, Jin ^a  

^a JILIN UNIVERSITY   (China)

Author keywords

Circular RNA DNA enzyme; Hammerhead ribozyme; In vitro selection; Regulation domain

Indexed keywords

DEOXYRIBONUCLEOTIDE; ENZYME; HAMMERHEAD RIBOZYME; RIBONUCLEASE A; RIBONUCLEOTIDE; RIBOZYME; RNA DNA ENZYME I; RNA DNA ENZYME II; RNA DNA ENZYME III; UNCLASSIFIED DRUG;

ARTICLE; ENZYME ACTIVITY; ENZYME REGULATION; ENZYME STABILITY; ENZYME SYNTHESIS; GENE TARGETING; IN VITRO STUDY; MOLECULE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RNA CLEAVAGE;

EID: 0036295104     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2002.6767     Document Type: Article

References (26)

1. In vitro splicing of the ribosomal RNA precursor of Tetrahymena: Involvement of a guanosine nucleotide in the excision of the intervening sequence
2. The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme
3. A small catalytic oligoribonucleotide
4. Simple RNA enzymes with new and highly specific endoribonuclease activities
5. DNA enzymes
6. Small catalytic RNAs
7. Ribozymes
8. Suppression of smooth muscle cell proliferation by a c-myc RNA-cleaving deoxyribozyme
9. Expression of ribozymes in gene transfer systems to modulate target RNA levels
10. Directed molecular evolution
11. In vitro genetics
12. In vitro genetic analysis of the Tetrahymena self-splicing intron
13. Directed evolution of nucleic acids by independent replication and selection
14. Inventing and improving ribozyme function: Rational design versus iterative selection methods
15. A DNA metalloenzyme with DNA ligase activity
16. Minimum ribonucleotide requirement for catalysis by the RNA hammer-head domain
17. Tech. Sight. Molecular biology. Making catalytic DNAs
18. The design and construction of a new nucleozyme
19. Enhancement of the cleavage rates of DNA-armed hammerhead ribozymes by various divalent metal ions
20. Initiation of protein synthesis by the eukaryotic translational apparatus on circular RNAs
21. Mechanism and utility of an RNA-Cleaving DNA enzyme
22. A general-purpose RNA-cleaving DNA enzyme
23. Ribozymes: Structure and mechanism in RNA catalysis
24. Cold adaptation of proteins. Purification, characterization, and sequence of the heat-labile subtilisin from the antarctic psychrophile Bacillus TA41
25. Rigidity of thermophilic enzymes
26. A small nucleolar RNA:ribozyme hybrid cleaves a nucleolar RNA target in vivo with near-perfect efficiency