The early kinetics of gentamicin uptake into the inner ear

International Tinnitus Journal

Volumn 8, Issue 1, 2002, Pages 27-29

  Hoffer, Michael E ^a   Allen, Keith ^a   Gottshall, Kim ^a   Moore, Robert ^a   Kopke, Richard D ^a   Wester, Derin ^a   Balaban, Carey ^a  

^a NAVAL MEDICAL CENTER SAN DIEGO   (United States)

Author keywords

Fluorescent polar immunoassay; Gentamicin; Mass spectrometry; M ni re's disease; Sustained release

Indexed keywords

GENTAMICIN;

ACCURACY; ANALYTIC METHOD; ANIMAL EXPERIMENT; ARTICLE; CHINCHILLA; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG DELIVERY SYSTEM; DRUG DETERMINATION; DRUG TISSUE LEVEL; DRUG UPTAKE; INNER EAR; MASS SPECTROMETRY; MENIERE DISEASE; NONHUMAN; PERILYMPH; PRIORITY JOURNAL; SUSTAINED DRUG RELEASE;

ANIMALS; ANTI-BACTERIAL AGENTS; CHINCHILLA; DELAYED-ACTION PREPARATIONS; EAR, INNER; GENTAMICINS; IMMUNOASSAY; MASS SPECTROMETRY; MENIERE'S DISEASE; PERILYMPH; PILOT PROJECTS;

EID: 0036289112     PISSN: 09465448     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (4)

1. Transtympanic vs. sustained release administration of gentamicin: Kinetics, morphology, and function
2. Gentamicin uptake by cochlear hair cells precedes hearing impairment during chronic treatment
3. Pharmacokinetics of gentamicin in perilymph and endolymph of the rat as determined by radioimmunoassay
4. Kinetics of gentamicin uptake and release in the rat. Comparison of inner ear tissues and fluids with other organs