Targeted deletion of the GP72 gene decreases the infectivity of Trypanosoma cruzi for mice and insect vectors

Journal of Parasitology

Volumn 88, Issue 3, 2002, Pages 489-493

  Basombrío, Miguel A ^a   Gómez, Laura ^a   Padilla, Angel M ^a   Ciaccio, Mirella ^a   Nozaki, Tomoyoshi ^a   Cross, George A M ^a  

^a UNIVERSIDAD NACIONAL DE SALTA   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; PROTEIN GP72; UNCLASSIFIED DRUG;

PARASITE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE CARRIER; EPIMASTIGOTE; FECES ANALYSIS; GENE DELETION; GENE MUTATION; IMMUNOCOMPETENCE; INFECTION; INOCULATION; INSECT; LATENT PERIOD; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PARASITE CULTIVATION; PARASITE ISOLATION; PHENOTYPE; POLYMERASE CHAIN REACTION; SEROLOGY; TRYPANOSOMA CRUZI; TRYPANOSOMIASIS;

ANIMALIA; INSECTA; PROTOZOA; TRIATOMA; TRIATOMA INFESTANS; TRYPANOSOMA; TRYPANOSOMA CRUZI;

EID: 0036287931     PISSN: 00223395     EISSN: None     Source Type: Journal    
DOI: 10.1645/0022-3395(2002)088[0489:tdotgg]2.0.co;2     Document Type: Article

References (20)

1. The calmodulin-ubiquitin-associated genes of Trypanososoma cruzi: Their identification and transcription
2. Intracelular growth and metacyclogenesis defects in Trypanosoma cruzi carrying a targeted deletion of a Tc 52 protein encoding allele
3. Measurement of adhesion and interiorization of Trypanosoma cruzi in mammalian cells
4. How do protozoan parasites survive inside macrophages?
5. Side effects of inmunization with live attenuated Trypanosoma cruzi in mice and rabbits
6. A simple protocol for the physical cleavage of Trypanosoma cruzi kinetoplast DNA present in blood samples and its use in polymerase chain reaction (PCR)-based diagnosis of Chagas disease
7. Infectivity of Trypanosoma cruzi metacyclic trypomastigotes from cultures kept in laboratory for different periods of time
8. Deletion of an inmunodominant Trypanosoma cruzi surface glycoprotein disrupts flagellum-cell adhesion
9. Trypanosoma cruzi: Spontaneous transformation by a Y strain variant in liquid medium
10. Gene replacement in parasitic protozoa
11. In vitro differentiating systems for the study of differential gene expression during Trypanosoma cruzi development
12. Stable transformation of Trypanosoma cruzi: Inactivation of the PUB 12.5 polyubiquitin gene by targeted gene disruption
13. Trypanosoma cruzi: Diferentiation after interaction of epimastigotes and Triatoma infestans intestinal homogenate
14. Complement resistance to parasites
15. Homologous recombination and stable transfection in the parasitic protozoan Trypanosoma brucei
16. LYT-1 protein is required for efficient in vitro infection by Trypanosoma cruzi
17. Inmunogenicity of the recombinant SAPA protein of Trypanosoma cruzi for mice
18. Gene deletion suggests a role for Trypanosoma cruzi surface glycoprotein GP72 in the insect and mammalian stages of the life cycle
19. 2 receptors
20. Trypanosomatid genetics