Novel haptoglobin insertion/deletion polymorphism is associated with the lipid profile and C-reactive protein (CRP) concentration

Clinical Chemistry and Laboratory Medicine

Volumn 40, Issue 5, 2002, Pages 469-474

  Wuyts, Birgitte ^a   Hetet, Gilles ^a   Grandchamp, Bernard ^a   Delanghe, Joris R ^a  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

Author keywords

C reactive protein (CRP); Capillary electrophoresis; Genetics; Haptoglobin; Lipids

Indexed keywords

APOLIPOPROTEIN A2; APOLIPOPROTEIN B; C REACTIVE PROTEIN; CHOLESTEROL; HAPTOGLOBIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; CARRIER PROTEIN; CITRATE BINDING TRANSPORT PROTEIN; CITRATE-BINDING TRANSPORT PROTEIN; LIPID;

ADULT; ALLELE; ARTICLE; BASE PAIRING; CHEMICAL PARAMETERS; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; FEMALE; GENE DELETION; GENE FREQUENCY; GENE INSERTION; GENETIC ASSOCIATION; GENETIC HETEROGENEITY; GENETIC POLYMORPHISM; GENOTYPE PHENOTYPE CORRELATION; HUMAN; INTRON; LIPID METABOLISM; LIPOPROTEIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; POPULATION GENETICS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; BELGIUM; BLOOD; GENE EXPRESSION REGULATION; GENETIC SCREENING; GENETICS; GENOTYPE; METHODOLOGY; MIDDLE AGED; PHENOTYPE;

INSERTION SEQUENCES;

ADULT; BELGIUM; CARRIER PROTEINS; FEMALE; GENE FREQUENCY; GENETIC HETEROGENEITY; GENETIC SCREENING; GENOTYPE; HAPTOGLOBINS; HUMANS; INTRONS; LIPIDS; MALE; MIDDLE AGED; MUTAGENESIS, INSERTIONAL; PHENOTYPE; POLYMORPHISM, GENETIC; SEQUENCE DELETION;

EID: 0036287824     PISSN: 14346621     EISSN: None     Source Type: Journal    
DOI: 10.1515/CCLM.2002.081     Document Type: Article

References (24)

1. Nature and metabolism of extracellular proteins
2. Haptoglobin
3. Biological and clinical significance of haptoglobin polymorphism in humans
4. Haptoglobin: The evolutionary product of duplication, unequal crossing over, and point mutation
5. Duplication within the haptoglobin Hp2 gene
6. Inheritance of haptoglobine subtypes
7. Amino-acid sequence of alpha-chains of human haptoglobins
8. Localization of the haptoglobin alpha and beta genes (HPA and HPB) to the human chromosome 16q22 by in situ hybridization
9. Amino-acid sequence of alpha-chains of human haptoglobins
10. DNA sequencing and chromosomal locations of human plasma protein genes
11. Zone electrophoresis in starch gels: Grouped variations in the serum proteins of normal human adults
12. Measurement of proteins with the Behring Nephelometer: A multicentre evaluation
13. New international reference preparation for proteins in human serum (RPPHS)
14. International Federation of Clinical Chemistry standardization project for measurements of apolipoproteins A-I and B. IV. Comparability of apolipoprotein B values by use of International Reference Material
15. International Federation of Clinical Chemistry standardization project for measurements of apolipoproteins A-I and B. III. Comparability of apolipoprotein A-I values by use of International Reference Material
16. Enzymatic determination of total cholesterol
17. Multicenter evaluation of a homogeneous assay for HDL-cholesterol without sample pretreatment
18. Quantitative determination of serum triglycerides by the use of enzymes
19. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge
20. Evaluation of C-reactive protein, a sensitive marker of inflammation, as a risk factor for stable coronary artery disease
21. Serum C-reactive protein, and fibrinogen concentrations, and self-reported angina pectoris, and myocardial infarction: Findings from National Health, and Nutrition Examination Survey III
22. Interleukin-6, and the acute phase response
23. C-reactive protein concentration in children: Relationship to adiposity and other cardiovascular risk factors
24. Molecular genetics and gene expression in atherosclerosis