Brain serotonin transporter binding characteristics of fluvoxamine and fluoxetine

Pharmacology Reviews and Communications

Volumn 12, Issue 2, 2002, Pages 129-137

  Hirano, Kazufumi ^a   Yamada, Shizuo ^a   Kimura, Ryohei ^a  

^a UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

Ex vivo binding; Fluoxetine; Fluvoxamine; Norepinephrine transporter; Serotonin transporter

Indexed keywords

FLUOXETINE; FLUVOXAMINE; NISOXETINE; PAROXETINE; SEROTONIN TRANSPORTER; SEROTONIN UPTAKE INHIBITOR;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DISSOCIATION CONSTANT; DRUG BINDING AND TRANSPORT; DRUG BINDING SITE; DRUG EFFECT; DRUG POTENCY; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEROTONIN BRAIN LEVEL;

EID: 0036287395     PISSN: 10288945     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Effect of fluvoxamine, a new antidepressant drug, on monoamine dynamics in the rat cerebral limbic system and its pharmacological characteristic
2. Effects of single and repeated oral administration of fluvoxamine on extracellular serotonin in the median raphe nucleus and dorsal hippocampus of the rat
3. Influence of dose and route of administration on the kinetics of fluoxetine and its metabolite norfluoxetine in the rat
4. Review of the animal pharmacology and pharmacokinetics of fluvoxamine
5. Metabolism and pharmacokinetics of selective serotonin reuptake inhibitors
6. Fluvoxamine. An updated review of its use in the management of adults with anxiety disorders
7. 3H]paroxetine binding to rat cortical membranes
8. Pharmacokinetics of selective serotonin reuptake inhibitors
9. Kinetics of receptor occupation and anticonvulsive effects of diazepam in rats
10. Protein measurement with the Folin phenol reagent
11. Sensitive one-step extraction procedure for column liquid chromatographic determination of fluvoxamine in human and rat plasma
12. Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites
13. Is therapeutic drug monitoring a case for optimizing clinical outcome and avoiding interactions of the selective serotonin reuptake inhibitors?
14. Graphic method for the determination and presentation of binding parameters in a complex system
15. Acute uptake inhibition increases extracellular serotonin in the rat forebrain
16. 3H]Nisoxetine: A new radioligand for norepinephrine uptake sites in brain
17. The receptor occupation and plasma concentration of NKY-722, a water-soluble dihydropyridine-type calcium antagonist, in spontaneously hypertensive rats
18. Prozac (fluoxetine, Lilly 110140), the first selective serotonin uptake inhibitor and an antidepressant drug: Twenty years since its first publication
19. 1-adrenoceptor subtype selectivity of KMD-3213 in rat tissues
20. Pharmacokinetics of amlodipine and its occupancy of calcium antagonist receptors
21. Integration of pharmacokinetics and pharmacodynamics in drug development-in vivo receptor occupancy by calcium antagonist and angiotensin II receptor antagonist
22. 3H]WB4101: Effect of 6-hydroxydopamine treatment