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Volumn 13, Issue 3, 2002, Pages 287-299
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Kinetics and hydrolysis mechanism of polymeric prodrugs containing ibuprofen, ketoprofen, and naproxen as pendent agents
a
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Author keywords
Enzymatic hydrolysis; Ibuprofen; Ketoprofen; Naproxen; Polymeric prodrug
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Indexed keywords
CARRAGEENAN;
ESTER DERIVATIVE;
ESTERASE;
IBUPROFEN;
KETOPROFEN;
METHACRYLIC ACID;
MONOMER;
NAPROXEN;
POLYMACON;
PRODRUG;
WATER;
2 HYDROXYETHYL METHACRYLATE;
METHACRYLIC ACID DERIVATIVE;
NONSTEROID ANTIINFLAMMATORY AGENT;
POLYMER;
ANTIINFLAMMATORY ACTIVITY;
ARTICLE;
CHEMICAL COMPOSITION;
CONTROLLED STUDY;
CORRELATION ANALYSIS;
COVALENT BOND;
DRUG HYDROLYSIS;
DRUG POTENCY;
DRUG SCREENING;
DRUG SOLUBILITY;
DRUG STRUCTURE;
DRUG SYNTHESIS;
EXPERIMENTAL TEST;
HYDROLYSIS KINETICS;
IN VITRO STUDY;
POLYMERIZATION;
PRIORITY JOURNAL;
STEREOSPECIFICITY;
STOMACH MUCOSA INJURY;
STRUCTURE ANALYSIS;
ANIMAL;
CHEMICALLY INDUCED DISORDER;
DRUG STABILITY;
EDEMA;
FEMALE;
HYDROLYSIS;
KINETICS;
PH;
RAT;
SOLUBILITY;
TREATMENT OUTCOME;
WISTAR RAT;
ANIMALS;
ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL;
DRUG STABILITY;
EDEMA;
FEMALE;
HYDROGEN-ION CONCENTRATION;
HYDROLYSIS;
IBUPROFEN;
KETOPROFEN;
KINETICS;
METHACRYLATES;
NAPROXEN;
POLYMERS;
PRODRUGS;
RATS;
RATS, WISTAR;
SOLUBILITY;
TREATMENT OUTCOME;
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EID: 0036286378
PISSN: 09205063
EISSN: None
Source Type: Journal
DOI: 10.1163/156856202320176538 Document Type: Article |
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Times cited : (16)
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References (21)
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