Reversal of diabetes-induced rat graft transplant coronary artery disease by metformin

Journal of Heart and Lung Transplantation

Volumn 21, Issue 6, 2002, Pages 637-643

  Cantin, Bernard ^a   Zhu, Dening ^a   Wen, Peizhong ^a   Panchal, Shyam N ^a   Dai, Xiaohong ^a   Gwathmey, Judith K ^b   Reaven, Gerald M ^a   Valantine, Hannah A ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; METFORMIN;

ALLOGRAFT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL DIAMETER; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DISEASE COURSE; DISEASE SEVERITY; DRUG EFFECT; DRUG EFFICACY; HEART INFARCTION; HEART TRANSPLANTATION; HISTOPATHOLOGY; ISOGRAFT; MALE; MORPHOMETRICS; NONHUMAN; PRIORITY JOURNAL; RAT; STREPTOZOCIN DIABETES; TREATMENT OUTCOME;

AMINOGLYCOSIDES; ANIMALS; ANTI-BACTERIAL AGENTS; CORONARY DISEASE; DIABETES MELLITUS, EXPERIMENTAL; DISEASE MODELS, ANIMAL; HEART TRANSPLANTATION; HYPOGLYCEMIC AGENTS; METFORMIN; RATS; TIME FACTORS;

EID: 0036283660     PISSN: 10532498     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1053-2498(01)00768-9     Document Type: Article

References (28)

1. The Registry of the International Society for Heart and Lung Transplantation: Seventeenth Official Report - 2000
2. Accelerated coronary vascular disease in the heart transplant patient: Coronary arteriographic findings
3. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)
4. Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34)
5. Diabetes and dyslipidemia. A new model for transplant coronary artery disease
6. Improved technique of heart transplantation in rats
7. A new rat model of type 2 diabetes: The fat-fed, streptozotocin-treated rat
8. Metformin
9. Cardiac transplantation in the rat. I. The effect of histocompatibility differences on graft arteriosclerosis
10. Considerations regarding the contributions of B cells to chronic allograft rejection in experimental animal models
11. Coronary endothelial dysfunction of isolated hearts subjected to prolonged cold storage: Patterns and contributing factors
12. Metformin improves vascular function in insulin-resistant rats
13. The influence of hypoglycaemic agents on the growth and metabolism of human endothelial cells
14. Rapamycin reverses chronic graft vascular disease in a novel cardiac allograft model
15. Experimental graft arteriosclerosis. I. The Lewis-to-F-344 allograft model
16. Evidence that graft coronary arteriosclerosis begins in the early phase after transplantation and progresses without chronic immunoreaction. Histopathological analysis using a retransplantation model
17. Cardiac transplantation in the rat. II. Alteration of the severity of donor graft arteriosclerosis by modulation of the host immune response
18. Alloantibody- and T cell-mediated immunity in the pathogenesis of transplant arteriosclerosis: Lack of progression to sclerotic lesions in B cell-deficient mice
19. Coronary atherosclerosis in transplanted mouse hearts. II. Importance of humoral immunity
20. The clinical significance of antibodies to human vascular endothelial cells after cardiac transplantation
21. Cold ischemic injury accelerates the progression to chronic rejection in a rat cardiac allograft model
22. Impact of proximal or midvessel discrete coronary artery stenoses on survival after heart transplantation
23. Management of cardiac allograft vasculopathy by transmyocardial laser revascularization
24. Transmyocardial laser revascularization in allograft coronary artery disease
25. Captopril and platelet-activating factor (PAF) antagonist prevent cardiac allograft vasculopathy in rats: Role of endogenous PAF and PAF-like compounds
26. New approach in the therapy of chronic rejection? ACE- and AT1-blocker reduce the development of chronic rejection after cardiac transplantation in a rat model
27. Effects of pravastatin on chronic rejection of rat cardiac allografts
28. Inhibition of endothelin-converting enzyme attenuates transplant vasculopathy and rejection in rat cardiac allografts