The in vitro and in vivo effects of 2-(4-morpholinyl)-8-phenylchromone (LY294002), a specific inhibitor of phosphatidylinositol 3′-kinase, in human colon cancer cells

Clinical Cancer Research

Volumn 8, Issue 6, 2002, Pages 1957-1963

  Semba, Shuho ^a   Itoh, Nanami ^a   Ito, Masafumi ^a   Harada, Masaru ^a   Yamakawa, Mitsunori ^a  

^a YAMAGATA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CASPASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CANCER MODEL; CARCINOMATOUS PERITONITIS; CELL PROLIFERATION; COLON CANCER; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INACTIVATION; FEMALE; GROWTH INHIBITION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; XENOGRAFT;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CASPASES; CELL DIVISION; CHROMONES; COLONIC NEOPLASMS; ENZYME INHIBITORS; FEMALE; HUMANS; IMMUNOENZYME TECHNIQUES; MICE; MICE, SCID; MORPHOLINES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED;

EID: 0036278927     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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