Characterization and semiquantitative analyses of pendrin expressed in normal and tumoral human thyroid tissues

Journal of Clinical Endocrinology and Metabolism

Volumn 87, Issue 4, 2002, Pages 1700-1707

  Porra, Valerie ^a,b,c   Bernier Valentin, Francoise ^a,c   Trouttet Masson, Severine ^a   Berger Dutrieux, Nicole ^a   Peix, Jean Louis ^a,b   Perrin, Agnes ^a   Selmi Ruby, Samia ^a,b,c   Rousset, Bernard ^a,c  

^a INSERM   (France)

^b EDOUARD HERRIOT HOSPITAL   (France)

^c Lyon Thyroid Tumor Bank Organization   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOSIDASE; PENDRIN; SUCROSE;

AMINO ACID SEQUENCE; ANION EXCHANGE; ANION TRANSPORT; ARTICLE; CARBOXY TERMINAL SEQUENCE; HUMAN; HUMAN TISSUE; INNER EAR; KIDNEY; MOLECULAR WEIGHT; PENDRED SYNDROME; PRIORITY JOURNAL; PROTEIN DENATURATION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; THYROID ADENOMA; THYROID FOLLICLE; THYROID GLAND; THYROID PAPILLARY CARCINOMA;

EID: 0036277794     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jcem.87.4.8372     Document Type: Article

References (19)

1. Progressive hearing loss, hypoplasia of the cochlea and widened vestibular aqueducts are very common features in Pendred's syndrome
2. Prevalence, age of onset, and natural history of thyroid disease in Pendred syndrome
3. Pendred syndrome is caused by mutations in a putative sulphate transporter gene (PDS)
4. Expression pattern of the mouse ortholog of the Pendred's syndrome gene (Pds) suggests a key role for pendrin in the inner ear
5. Pendrin: An apical Cl(-)/OH(-)/HCO(3)(-) exchanger in the kidney cortex
6. - symporter and Pendred syndrome genes in trophoblast
7. Na/I symporter and Pendred syndrome gene and protein expressions in human extra-thyroidal tissues
8. Pendrin, the protein encoded by the Pendred syndrome gene (PDS), is an apical porter of iodide in the thyroid and is regulated by thyroglobulin in FRTL-5 cells
9. The Pendred syndrome gene encodes a chloride-iodide transport protein
10. Human pendrin expressed in Xenopus laevis oocytes mediates chloride/formate exchange
11. Pendrin, encoded by the Pendred syndrome gene, resides in the apical region of renal intercalated cells and mediates bicarbonate secretion
12. Expression of pendrin and the Pendred syndrome (PDS) gene in human thyroid
13. Culture of dendritic cells from a nonlymphoid organ, the thyroid gland: Evidence for TNFα-dependent phenotypic changes of thyroid-derived dendritic cells
14. Single step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction
15. Isozymes of the Na-K-ATPase: Heterogeneity in structure, diversity in function
16. Phosphofructokinase in normal thyroid tissue and thyroid neoplasms
17. Pyruvate kinase in normal human thyroid tissue and thyroid neoplasms
18. Increased activities of thymidylate synthetase and thymidine kinase in human thyroid tumors
19. Marked increases in cathepsin B and L activities distinguish papillary carcinoma of the thyroid from normal thyroid or thyroid with non-neoplastic disease