Issues in design and analysis of a randomized clinical trial to assess the safety of dental amalgam restorations in children

Controlled Clinical Trials

Volumn 23, Issue 3, 2002, Pages 301-320

  DeRouen, Timothy A ^a   Leroux, Brian G ^a   Martin, Michael D ^a   Townes, Brenda D ^b   Woods, James S ^a,c   Leitão, Jorge ^d   Castro Caldas, Alexandre ^e   Braveman, Norman ^f  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c BATTELLE MEMORIAL INSTITUTE   (United States)

^d UNIVERSITY OF LISBON   (Portugal)

^e INSTITUTO DE MEDICINA MOLECULAR   (Portugal)

^f NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

Author keywords

Children; Dental amalgam; Interim analyses; Mercury; Multiple endpoints; Neurobehavioral test; Safety

Indexed keywords

DENTAL ALLOY; MERCURY;

ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DENTAL CARE; EXPOSURE; FEMALE; FOLLOW UP; HUMAN; INFORMED CONSENT; MAJOR CLINICAL STUDY; MALE; MEDICAL ETHICS; METHODOLOGY; RANDOMIZED CONTROLLED TRIAL; SAFETY; SAMPLE SIZE; SCHOOL; SCHOOL CHILD; SOCIOECONOMICS;

CHILD; CHILD BEHAVIOR DISORDERS; DENTAL AMALGAM; DENTAL CARE FOR CHILDREN; FEMALE; HUMANS; MALE; MERCURY; PORTUGAL; RESEARCH DESIGN;

EID: 0036277093     PISSN: 01972456     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-2456(01)00206-9     Document Type: Article

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