Cytotoxicity of flutamide and 2-hydroxyflutamide and their effects on CYP1A2 mRNA in primary rat hepatocytes

Acta Pharmacologica Sinica

Volumn 23, Issue 6, 2002, Pages 562-566

  Wang, Hai Xue ^a   Ma, Xiao Chao ^a   Deng, Qiao Lin ^a   Li, Duan ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

2 hydroxyflutamide; Cytochrome P 450 CYP1A2; Cytotoxicity; Flutamide

Indexed keywords

2 HYDROXYFLUTAMIDE; ASPARTATE AMINOTRANSFERASE; CYTOCHROME P450 1A2; DRUG METABOLITE; FLUTAMIDE; GLUTATHIONE; LACTATE DEHYDROGENASE; MESSENGER RNA; TRYPAN BLUE; UNCLASSIFIED DRUG; ANTIANDROGEN; DRUG DERIVATIVE; HYDROXYFLUTAMIDE;

ANIMAL CELL; ARTICLE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; CYTOTOXICITY; DRUG EFFECT; ENZYME ACTIVITY; LIVER CELL; MALE; NONHUMAN; NORTHERN BLOTTING; PROTEIN EXPRESSION; PROTEIN INDUCTION; RAT; ANIMAL; BIOSYNTHESIS; CELL CULTURE; ENZYMOLOGY; GENETICS; SPRAGUE DAWLEY RAT;

ANDROGEN ANTAGONISTS; ANIMALS; CELLS, CULTURED; CYTOCHROME P-450 CYP1A2; FLUTAMIDE; HEPATOCYTES; MALE; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER;

EID: 0036276743     PISSN: 16714083     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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