The production of human papillomavirus type 16 L1 vaccine product from Escherichia coli inclusion bodies

Bioprocess and Biosystems Engineering

Volumn 25, Issue 2, 2002, Pages 121-128

  Lai, W B ^a   Middelberg, A P J ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Inclusion body; Papillomavirus; Process development; Refolding

Indexed keywords

ADSORBENT; ARGININE; BUFFER; CAPSID PROTEIN; DETERGENT; EPITOPE; MONOCLONAL ANTIBODY; RECOMBINANT PROTEIN; VIRUS VACCINE;

ANALYTIC METHOD; ANTIGEN BINDING; ANTIGENICITY; ARTICLE; CELL INCLUSION; CONCENTRATION (PARAMETERS); CONFORMATION; CONTROLLED STUDY; DIAFILTRATION; DIALYSIS; DILUTION; ENZYME LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI; FEASIBILITY STUDY; IMMOBILIZED METAL AFFINITY CHROMATOGRAPHY; IMMUNOGENICITY; INTERMETHOD COMPARISON; ION EXCHANGE CHROMATOGRAPHY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DENATURATION; PROTEIN EXPRESSION; PROTEIN PROCESSING; PROTEIN PURIFICATION; SCALE UP; VACCINE PRODUCTION; WART VIRUS;

DNA VIRUSES; ESCHERICHIA COLI; HUMAN PAPILLOMAVIRUS; HUMAN PAPILLOMAVIRUS TYPE 16; HUMAN PAPILLOMAVIRUS TYPES; NEGIBACTERIA; PAPILLOMAVIRUS;

EID: 0036275524     PISSN: 16157591     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00449-002-0289-6     Document Type: Article

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