Truncation of merozoite surface protein 3 disrupts its trafficking and that of acidic-basic repeat protein to the surface of Plasmodium falciparum merozoites

Molecular Microbiology

Volumn 43, Issue 6, 2002, Pages 1401-1411

  Mills, Kerry E ^a   Pearce, J Andrew ^a   Crabb, Brendan S ^a   Cowman, Alan F ^a  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; GLUTAMIC ACID; LEUCINE; MEROZOITE SURFACE PROTEIN 3; PROTOZOAL PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL SURFACE; CELL VACUOLE; CONTROLLED STUDY; ERYTHROCYTE; GENE DISRUPTION; HOMOLOGOUS RECOMBINATION; MEROZOITE; NONHUMAN; NUCLEOTIDE REPEAT; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; PROTOZOAL GENETICS;

ANIMALS; ANTIGENS, PROTOZOAN; ANTIGENS, SURFACE; ERYTHROCYTES; GENE TARGETING; GENES, PROTOZOAN; HUMANS; MALARIA, FALCIPARUM; PLASMODIUM FALCIPARUM; PROTOZOAN PROTEINS; RECOMBINATION, GENETIC; REPETITIVE SEQUENCES, NUCLEIC ACID; VACUOLES;

ABRA; PLASMODIUM FALCIPARUM; PROTOZOA;

EID: 0036272127     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.2002.02834.x     Document Type: Article

References (44)

1. Role of amphipathic helixes in HDL structure/function
2. Characterization of an S antigen synthesized by several isolates of Plasmodium falciparum
3. Human malaria in immunocompromised mice: An in vivo model to study defense mechanisms against Plasmodium falciparum
4. RAP1 controls rhoptry targeting of RAP2 in the malaria parasite Plasmodium falciparum
5. Merozoite surface protein 8 of Plasmodium falciparum contains two epidermal growth factor-like domains
6. A single fragment of a malaria merozoite surface protein remains on the parasite during red cell invasion and is the target of invasion-inhibiting antibodies
7. Separation of large DNA molecules by contour clamped homogeneous electric fields
8. Mapping of the region predominantly recognized by antibodies to the Plasmodium falciparum merozoite surface antigen MSA 1
9. Chromosome size polymorphisms in Plasmodium falciparum can involve deletions and are frequent in natural parasite populations
10. A P-glycoprotein homologue of Plasmodium falciparum is localized on the digestive vacuole
11. Characterization of promoters and stable transfection by homologous and nonhomologous recombination in Plasmodium falciparum
12. Targeted gene disruption shows that knobs enable malaria-infected red cells to cytoadhere under physiological shear stress
13. Evidence for a switching mechanism in the invasion of erythrocytes by Plasmodium falciparum
14. Glycophorin B as an EBA-175 independent Plasmodium falciparum receptor of human erythrocytes
15. Genetic polymorphism and natural selection in the malaria parasite Plasmodium falciparum
16. Plasmodium vivax merozoite surface protein-3 contains coiled-coil motifs in an alanine-rich central domain
17. Cytoplasmic ribonucleoprotein complexes containing human LINE-1 protein and RNA
18. The three major antigens on the surface of Plasmodium falciparum merozoites are derived from a single high molecular weight precursor
19. Primary structure of the precursor to the three major surface antigens of Plasmodium falciparum merozoites
20. The malarial merozoite surface: A 140,000 MW protein antigenically unrelated to other surface components on Plasmodium knowlesi merozoites
21. Disruption of the C-terminal region of EBA-175 in the Dd2/Nm clone of Plasmodium falciparum does not affect erythrocyte invasion
22. 19) variants secreted from Saccharomyces cerevisiae
23. Expression and characterisation of Plasmodium falciparum acidic basic repeat antigen expressed in Escherichia coli
24. Identification of an endoplasmic reticulum-resident calcium-binding protein with multiple EF-hand motifs in asexual stages of Plasmodium falciparum
25. Synchronization of Plasmodium falciparum erythrocytic stages in culture
26. Interaction between PRP11 and SPP91 yeast splicing factors and characterization of a PRP9-PRP11-SPP91 complex
27. Coiled coils: New structures and new functions
28. Conservation of structural motifs and antigenic diversity in the Plasmodium falciparum merozoite surface protein-3 (MSP-3)
29. Molecular variation in a novel polymorphic antigen associated with Plasmodium falciparum merozoites
30. A second merozoite surface protein (MSP-4) of Plasmodium falciparum that contains an epidermal growth factor-like domain
31. Close linkage of three merozoite surface protein genes on chromosome 2 of Plasmodium falciparum
32. Solution structure of a polypeptide containing four heptad repeat units from a merozoite surface antigen of Plasmodium falciparum
33. Plasmodium falciparum: Chymotryptic-like proteolysis associated with a 101-kDa acidic-basic repeat antigen
34. Merozoite surface protein-3: A malaria protein inducing antibodies that promote Plasmodium falciparum killing by cooperation with blood monocytes
35. A novel merozoite surface antigen of Plasmodium falciparum (MSP-3) identified by cellular-antibody cooperative mechanism antigenicity and biological activity of antibodies
36. Plasmodium falciparum field isolates commonly use erythrocyte invasion pathways that are independent of sialic acid residues of glycophorin A
37. A malaria invasion receptor, the 175-kilodalton erythrocyte binding antigen of Plasmodium falciparum recognizes the terminal Neu5Ac (alpha2-3) Gal- sequences of glycophorin A
38. Targeted disruption of an erythrocyte binding antigen in Plasmodium falciparum is associated with a switch toward a sialic acid independent pathway of invasion
39. Identification and characterization of an escorter for two secretory adhesins in Toxoplasma gondii
40. Identification of two integral membrane proteins of Plasmodium falciparum
41. Human malaria parasites in continuous culture
42. The merozoite surface protein 6 gene codes for a 36 kDa protein associated with the Plasmodium falciparum merozoite surface protein-1 complex
43. Transformation of Plasmodium falciparum malaria parasites by homologous integration of plasmids that confer resistance to pyrimethamine