Molecular modeling of eluted peptides from DQ6 molecules (DQB1*0602 and DQB1*0604) negatively and positively associated with type 1 diabetes

Annals of the New York Academy of Sciences

Volumn 958, Issue , 2002, Pages 317-320

  Sanjeevi, C B ^a   Lybrand, T P ^b   Stevanovic, S ^c   Rammensee, H G ^c,d  

^a KAROLINSKA INSTITUTE   (Sweden)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF TÜBINGEN   (Germany)

^d KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

HLA DQ6; IDDM; Molecular modeling; Peptide motif

Indexed keywords

HLA DQ ANTIGEN;

AMINO ACID SEQUENCE; ANIMAL CELL; CONFERENCE PAPER; DISEASE ASSOCIATION; INSULIN DEPENDENT DIABETES MELLITUS; MOLECULAR MODEL; NONHUMAN; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SCREENING; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY;

ANIMALIA; BOVINAE;

EID: 0036268874     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2002.tb02995.x     Document Type: Conference Paper

References (10)

1. Polymorphic amino acids variations in HLA-DQ are associated with systematic physical property changes and occurrence of insulin-dependent diabetes mellitus
2. Characterization of a novel reverse-orientation model fo a peptide/MHC complex associated with type 1 diabetes mellitus
3. Structure of a human insulin peptide-HLA-DQ8 complex and susceptibility to type I diabetes
4. Analysis of critical residues of DQ6 molecules associated with insulin-dependent diabetes
5. Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide
6. Prediction of protein side-chain rotamers from a backbone-dependent rotamer library: A new homology modeling tool
7. Novel method for the rapid evaluation of packing in protein structures
8. The midas display system
9. A new force field for molecular mechanical simulation of nucleic acids and proteins