Characterization of the dexniguldipine binding site in the multidrug resistance-related transport protein P-glycoprotein by photoaffinity labeling and mass spectrometry

Molecular Pharmacology

Volumn 61, Issue 6, 2002, Pages 1366-1376

  Borchers, Christoph ^a,c   Boer, Rainer ^b   Klemm, Kurt ^b   Figala, Volker ^b   Denzinger, Thomas ^a   Ulrich, Wolf Rüdiger ^b   Haas, Sabine ^b   Ise, Wolfgang ^b   Gekeler, Volker ^b   Przybylski, Michael ^a  

^a UNIVERSITY OF KONSTANZ   (Germany)

^b ALTANA PHARMA AG   (Germany)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZIDOPINE; B 9209005; DEXNIGULDIPINE; GLYCOPROTEIN P; LECTIN; TRYPSIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CONTROLLED STUDY; DRUG SENSITIZATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MULTIDRUG RESISTANCE; PHOTOAFFINITY LABELING; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; T LYMPHOBLAST;

ANTINEOPLASTIC AGENTS; AZIDES; BINDING SITES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIHYDROPYRIDINES; HUMANS; MASS SPECTROMETRY; P-GLYCOPROTEIN; PEPTIDE FRAGMENTS; PHOTOAFFINITY LABELS; TRITIUM; TRYPSIN; TUMOR CELLS, CULTURED;

EID: 0036265334     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.61.6.1366     Document Type: Article

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