Thromboxane synthase immunohistochemistry in inflammatory bowel disease

Journal of Clinical Pathology

Volumn 55, Issue 5, 2002, Pages 367-370

  Carty, E ^a   Rampton, D S ^a   Nickols, C ^b   Feakins, R M ^b  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

THROMBOXANE SYNTHASE;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; COLON MUCOSA; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ACTIVITY; ENDOSCOPY; ENTERITIS; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTESTINE MUCOSA; LAMINA PROPRIA; MALE; MUCOSA INFLAMMATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECTUM MUCOSA;

EID: 0036264583     PISSN: 00219746     EISSN: None     Source Type: Journal    
DOI: 10.1136/jcp.55.5.367     Document Type: Article

References (40)

1. Thromboxanes: A new group of biologically active compounds derived from prostaglandin endoperoxides
2. Review article: Thromboxanes in inflammatory bowel disease - Pathogenic and therapeutic implications
3. Inflammatory mediator changes in cotton-top tamarins (CTT) after SC-41930 anti-colitic therapy
4. Metabolism of arachidonic acid in acetic acid colitis in rats. Similarity to human inflammatory bowel disease
5. Participation of thromboxane and other eicosanoid synthesis in the course of experimental inflammatory colitis
6. Effect of ingestion of eicosapentaenoic acid ethyl ester on carrageenan-induced colitis in guinea pigs
7. Prostanoid synthesis by cultured intestinal epithelial and mononuclear cells in inflammatory bowel disease
8. Biosynthesis of lipoxygenase and cyclo-oxygenase products from [14C]-arachidonic acid by human colonic mucosa
9. Prostaglandins and the gastrointestinal mucosa: Are they important in its function, disease, or treatment?
10. Imbalance of prostacyclin and thromboxane synthesis in Crohn's disease
11. In vivo profiles of eicosanoids in ulcerative colitis, Crohn's colitis, and Clostridium difficile colitis
12. Picotamide inhibition of excess in vitro thromboxane B2 release by colorectal mucosa in inflammatory bowel disease
13. Ridogrel, a dual thromboxane synthase inhibitor and receptor antagonist: Anti-inflammatory profile in inflammatory bowel disease
14. Effects of thromboxane synthase inhibition on in vivo release of inflammatory mediators in chronic ulcerative colitis
15. Ridogrel for the treatment of mild to moderate ulcerative colitis
16. Ridogrel for the treatment of mild to moderate ulcerative colitis. A placebo controlled trial
17. Variation between observers in describing mucosal changes in proctocolitis
18. Indium 111-granulocyte scanning in the assessment of disease extent and disease activity in inflammatory bowel disease. A comparison with colonoscopy, histology, and fecal indium 111-granulocyte excretion
19. Production and characterization of polyclonal and monoclonal antibodies against human thromboxane synthase
20. Immunohistochemical localisation of thromboxane synthase in human intrauterine tissue
21. Thromboembolism in inflammatory bowel disease: Role of platelets
22. Chemotactic activity of thromboxane B2, prostaglandins and their metabolites for polymorphonuclear leucocytes
23. Thromboxane A2 induces leukotriene B4 synthesis that in turn mediates neutrophil diapedesis via CD 18 activation
24. Thromboxane-induced neutrophil adhesion to pulmonary microvascular and aortic endothelium is regulated by CD18
25. Endothelial-secreted arachidonic acid metabolites modulate polymorphonuclear leukocyte chemotaxis and diapedesis in vitro
26. Thromboxane A2 receptor is highly expressed in mouse immature thymocytes and mediates DNA fragmentation and apoptosis
27. Effect of inhibitors of arachidonic acid metabolism on mitogenesis in human lymphocytes: Possible role of thromboxanes and products of the lipoxygenase pathway
28. Vasoconstriction with thromboxane A2 induces ulceration of the gastric mucosa
29. Hypersensitive prostaglandin and thromboxane response to hormones in rabbit colitis
30. Platelets circulate in an activated state in inflammatory bowel disease
31. Mucosal capillary thrombi in rectal biopsies
32. Pathogenesis of Crohn's disease: Multifacal gastrointestinal infarction
33. Isolation and characterization of thromboxane synthase from human platelets as a cytochrome P-450 enzyme
34. Metabolism and action of the prostaglandin endoperoxide PGH2 in rat kidney
35. Diversion of prostaglandin endoperoxide metabolism by selective inhibition of thromboxane A2 biosynthesis in lung, spleen or platelets
36. Endogenous formation of the prostaglandin endoperoxide metabolite, thromboxane B2, by brain tissue
37. Identification of an enzyme in platelet microsomes which generates thromboxane A2 from prostaglandin endoperoxides
38. Transformation of arachidonic acid into thromboxane B2 by the homogenates of activated macrophages
39. Thromboxane A2 biosynthesis in human lung fibroblasts WI-38
40. Localization of thromboxane synthase in human tissues by monoclonal antibody Tu 300