Pramipexole in patients with Parkinson's disease and marked drug resistant tremor: A randomised, double blind, placebo controlled multicentre study

Journal of Neurology Neurosurgery and Psychiatry

Volumn 72, Issue 6, 2002, Pages 713-720

  Pogarell, Oliver ^a   Gasser, T ^b   Van Hilten, J J ^c   Spieker, S ^d   Pollentier, S ^e   Meier, D ^e   Oertel, W H ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^d UNIVERSITY OF TÜBINGEN   (Germany)

^e BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PLACEBO; PRAMIPEXOLE;

ABDOMINAL PAIN; ADULT; AGED; ARTICLE; BRAIN DEPTH STIMULATION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG EFFICACY; FATIGUE; FEMALE; HEADACHE; HUMAN; INSOMNIA; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NAUSEA; PARKINSON DISEASE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; RISK BENEFIT ANALYSIS; TREMOR; VERTIGO;

ADMINISTRATION, ORAL; ADULT; AGED; AGED, 80 AND OVER; ANTIPARKINSON AGENTS; BENZOTHIAZOLES; DOUBLE-BLIND METHOD; DRUG RESISTANCE; ELECTROMYOGRAPHY; FEMALE; HUMANS; MALE; MIDDLE AGED; PARKINSON DISEASE; PLACEBOS; THIAZOLES; TREATMENT OUTCOME; TREMOR;

EID: 0036262495     PISSN: 00223050     EISSN: None     Source Type: Journal    
DOI: 10.1136/jnnp.72.6.713     Document Type: Article

References (26)

1. Clinical manifestations of Parkinson's disease
2. Parkinsonism
3. Chronic electrical stimulation of the ventralis intermedius nucleus of the thalamus as a treatment of movement disorders
4. High frequency unilateral thalamic stimulation in the treatment of essential and parkinsonian tremor
5. Treatment of tremor in Parkinson's disease by subthalamic nucleus stimulation
6. Electrical stimulation of the subthalamic nucleus in advanced Parkinson's disease
7. 2 receptor agonist
8. Pramipexole binding and activation of cloned and expressed dopamine D2, D3 and D4 receptors
9. Pharmacology of pramipexole, a dopamine D3-preferring agonist useful in treating Parkinsan's disease
10. Double-blind comparison of pramipexole and bromocriptine treatment with placebo in advanced Parkinson's disease
11. Clinical evaluation of pramipexole in advanced Parkinson's disease: Results of a double-blind, placebo-controlled, parallel-group study
12. Safety and efficacy of pramipexole in early Parkinson's disease: A randomized dose-ranging study
13. Efficacy of pramipexole, a novel dopamine agonist, as monotherapy in mild to moderate Parkinson's disease
14. Efficacy, safety, and tolerance of the non-ergoline dopamine agonist pramipexole in the treatment of advanced Parkinson's disease: A double blind, placebo controlled, randomised, multicentre study
15. Falling asleep at the wheel: Motor vehicle mishaps in persons taking pramipexole and ropinirole
16. A non-ergot dopamine agonist, pramipexole, in the therapy of advanced Parkinson's disease: Improvement of Parkinsonian symptoms and treatment associated complications: A review of three studies
17. Pramipexole, a non-ergot dopamine agonist, is effective against rest tremor in intermediate to advanced Parkinson's disease
18. The relevance of Lewy body to the pathogenesis of idiopathic Parkinson's disease
19. Tremors in Parkinson's disease: Symptom analysis and rating
20. Assessing tremor severity with long-term tremor recordings
21. Reliability, specificity and sensitivity of long-term tremor recordings
22. Parkinson's disease: An open label trial of pergolide in patients failing bromocriptine therapy
23. A multicenter double-blind placebo-controlled trial of pergolide as an adjunct to sinemet® in Parkinson's disease
24. Comparison of lisuride and bromocriptine in the treatment of advanced Parkinson's disease
25. Tremorlytic activity of budipine: A quantitative study with long-term tremor recordings
26. Tremorlytic activity of budipine in Parkinsons disease