Cellular pathology changes in rat skin following intradermal injection of nerve growth factor: Neutrophil-dependent and -independent events

Journal of Pathology

Volumn 197, Issue 2, 2002, Pages 245-255

  Foster, Paul A ^a,c   Wicks, Sharon ^a   Foster, Martyn ^b   Brain, Susan D ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b Aventis Pharma Ltd   (United Kingdom)

^c ROYAL LONDON HOSPITAL   (United Kingdom)

Author keywords

Hyperalgesia; Inflammation; Macrophage; Muscle regeneration; Neutrophil; NGF; Rat; Skin

Indexed keywords

EOSIN; FIBRIN; GRANULOCYTE ANTIBODY; HEMATOXYLIN; NERVE GROWTH FACTOR; NEUROTROPIN; SODIUM CHLORIDE;

ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL MATURATION; CELL NUCLEUS; CELL POPULATION; CELL PROLIFERATION; CELL STRUCTURE; CELL SURVIVAL; CONTROLLED STUDY; HISTOPATHOLOGY; HYPERALGESIA; INFLAMMATION; INFLAMMATORY CELL; LYMPHOCYTE; MACROPHAGE; MALE; MEDIATOR; MUSCLE CELL; MUSCLE REGENERATION; NEUTROPHIL; NONHUMAN; PAIN; PRIORITY JOURNAL; RAT; SARCOLEMMA; SKIN EDEMA; SKIN INJURY; TISSUE INJURY; WOUND HEALING;

ANIMALS; DERMATITIS; INJECTIONS, INTRADERMAL; MALE; MUSCULAR DISEASES; NERVE GROWTH FACTORS; NEUTROPHIL INFILTRATION; NEUTROPHILS; RATS; RATS, WISTAR; SKIN;

EID: 0036262118     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/path.1111     Document Type: Article

References (37)

1. Nerve growth factor
2. Neurotrophic factors and neuronal death
3. NGF as a mediator of inflammatory pain
4. The biological effects of endogenous nerve growth factor on adult sensory neurons revealed by a trkA-IgG fusion molecule
5. Brain-derived neurotrophic factor promotes the survival and sprouting of serotonergic axons in rat brain
6. Local control of neurite sprouting in cultured sympathetic neurons by nerve growth factor
7. Timing and site of nerve growth factor synthesis in developing skin in relation to innervation and expression of the receptor
8. Over-expression of nerve growth factor in epidermis of transgenic mice causes hypertrophy of the peripheral nervous system
9. Expression and function of nerve growth factor and nerve growth factor receptor on cultured keratinocytes
10. Growth-regulated synthesis and secretion of biologically active nerve growth factor by human keratinocytes
11. Nerve growth factor levels in developing rat skin: Upregulation following skin wounding
12. Circulating nerve growth factor levels are increased in humans with allergic diseases and asthma
13. Nerve growth factor in the synovial fluid of patients with chronic arthritis
14. Nerve growth factor: A chemotactic factor for polymorphonuclear leukocytes in vivo
15. Nerve growth factor in nociception
16. Nerve growth factor induced hyperalgesia in the rat hind paw is dependent on circulating neutrophils
17. Nerve growth factor: Stimulation of polymorphonuclear leukocyte chemotaxis in vitro
18. Psoriatic keratinocytes express high levels of nerve growth factor
19. Nerve growth factor accelerates the early cellular events associated with wound healing
20. Role of nerve growth factor in cutaneous wound healing: Accelerating effects in normal and healing-impaired diabetic mice
21. Nerve growth factor: Acceleration of the rate of wound healing in mice
22. 6-(1-iminoethyl)lysine on zymosan-induced plasma extravasation in rat skin
23. The non-specific nature of the myocardial wavy fibre
24. Untersuchungen uber rheumatische Myokarditis
25. An ultrastructural study of the origin and function of basophilic degeneration in human cardiac muscle: Cardiac colloid type 1
26. The role of the polymorphonuclear leukocyte in hyperalgesia
27. Human neutrophils specifically interact with human monocyte-derived macrophage monolayers
28. Functional properties of murine macrophages promoted by nerve growth factor
29. Reduced hyperalgesia in nerve-injured WLD mice: Relationship to nerve fiber phagocytosis, axonal degeneration, and regeneration in normal mice
30. Depletion of macrophages reduces axonal degeneration and hyperalgesia following nerve injury
31. Reperfusion injury: Experimental evidence and clinical implications
32. The effect of systemically administered recombinant human nerve growth factor in healthy human subjects
33. Intradermal recombinant human nerve growth factor induces pressure allodynia and lowered heat-pain threshold in humans
34. Development of approaches to improve the healing following muscle contusion
35. Use of growth factors to improve muscle healing after strain injury
36. Growth factors improve muscle healing in vivo