Sequence analysis of the pro-opiomelanocortin (POMC) gene in obese/diabetic Japanese

International Journal of Obesity

Volumn 26, Issue 5, 2002, Pages 730-731

  Ohshiro, Y ^a   Ueda, K ^a   Wakasaki, H ^a   Kosaka, M ^a   Nishi, M ^a   Sasaki, H ^a   Takasu, N ^b   Nanjo, K ^a  

^a WAKAYAMA UNIVERSITY   (Japan)

^b UNIVERSITY OF THE RYUKYUS   (Japan)

Author keywords

DNA sequence analysis; Japanese; Morbid obesity; Mutation; Pro opiomelanocortin

Indexed keywords

PROOPIOMELANOCORTIN;

ADULT; ARTICLE; BODY MASS; DIABETES MELLITUS; FEMALE; GENE MUTATION; GENE SEQUENCE; GENOTYPE; HUMAN; JAPAN; MAJOR CLINICAL STUDY; MALE; OBESITY; PRIORITY JOURNAL;

BODY MASS INDEX; DIABETES MELLITUS; DIABETES MELLITUS, TYPE 2; FEMALE; GENE FREQUENCY; HUMANS; JAPAN; MALE; MIDDLE AGED; MUTATION; OBESITY; OBESITY, MORBID; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; PRO-OPIOMELANOCORTIN; SEQUENCE ANALYSIS, DNA;

EID: 0036261336     PISSN: 03070565     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.ijo.0801950     Document Type: Article

References (10)

1. Genetics of body-weight regulation
2. Targeted disruption of the melanocortin-4 receptor results in obesity in mice
3. Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans
4. A frameshift mutation in MC4R associated with dominantly inherited human obesity
5. A frameshift mutation in human MC4R is associated with a dominant form of obesity
6. Medicinal strategies in the treatment of obesity
7. Molecular scanning for mutations in the melanocortin-4 receptor gene in obese/diabetic Japanese
8. A polymorphic marker in the leptin gene associated with Japanese morbid obesity
9. Systematic mutation screening of the pro-opiomelanocortin gene: Identification of several genetic variants including three different insertions, one nonsense and two missense point mutations in probands of different weight extremes
10. Complete nucleotide sequence of the human corticotropin-β-lipotropin precursor gene