Dual regulation of cardiac Na+-K+ pumps and CFTR Cl- channels by protein kinases A and C

Pflugers Archiv European Journal of Physiology

Volumn 444, Issue 1-2, 2002, Pages 251-262

  Erlenkamp, Simone ^a   Glitsch, Helfried G ^b   Kockskämper, Jens ^a,b,c  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b RUHR UNIVERSITY BOCHUM   (Germany)

^c LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

CFTR Cl channel; Differences in regulation; Na+ K+ pump; Protein kinase A; Protein kinase C; Ventricular myocyte

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ADRENERGIC RECEPTOR; CHELERYTHRINE; CHLORIDE CHANNEL; CYCLIC AMP DEPENDENT PROTEIN KINASE; DIHYDROOUABAIN; FORSKOLIN; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PHORBOL DIBUTYRATE; PROTEIN KINASE C; PURINE RECEPTOR; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ADRENERGIC STIMULATION; ANIMAL CELL; ARTICLE; CHLORIDE CURRENT; CONTROLLED STUDY; ENZYME ACTIVITY; GUINEA PIG; HEART MUSCLE CELL; HEART VENTRICLE; MEMBRANE CURRENT; MEMBRANE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; SYMPATHETIC TONE; VOLTAGE CLAMP;

ALKALOIDS; ANIMALS; BENZOPHENANTHRIDINES; CARDIAC GLYCOSIDES; CELL MEMBRANE; CELL SEPARATION; CHLORIDE CHANNELS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; ENZYME ACTIVATORS; ENZYME INHIBITORS; FORSKOLIN; GUINEA PIGS; MYOCARDIUM; NA(+)-K(+)-EXCHANGING ATPASE; PHENANTHRIDINES; PHORBOL 12,13-DIBUTYRATE; PROTEIN KINASE C; RECEPTOR CROSS-TALK;

EID: 0036261227     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00424-002-0802-4     Document Type: Article

References (54)

1. Chloride conductance regulated by cyclic AMP-dependent protein kinase in cardiac myocytes
2. Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinsulfonamide (H-89), of PC12D pheochromocytoma cells
3. Unitary chloride channels activated by protein kinase C in guinea pig ventricular myocytes
4. Regulation of the CFTR channel by phosphorylation
5. v1.2) and antagonizes channel phosphorylation by cAMP-dependent protein kinase
6. The A-kinase anchor protein MAP2B and cAMP-dependent protein kinase are associated with class C L-type calcium channels in neurons
7. v1.2
8. 2+ current to nitric oxide in frog ventricular myocytes
9. + pump cycle during β-adrenergic stimulation of adult rat cardiac myocytes
10. - channels in mouse heart: A novel, alternative pathway for CFTR regulation
11. Calculator programs for computing the composition of the solutions containing multiple metals and ligands used for experiments in skinned muscle cells
12. Conformation-dependent phosphorylation of Na,K-ATPase by protein kinase A and protein kinase C
13. Steady-state current-voltage relationship of the Na/K pump in guinea pig ventricular myocytes
14. Control of CFTR channel gating by phosphorylation and nucleotide hydrolysis
15. The CFTR chloride channel of mammalian heart
16. + pump current in guinea-pig ventricular myocytes by a cAMP-dependent PKA pathway
17. Two functionally different Na/K pumps in cardiac ventricular myocytes
18. 2+ channels requires membrane targeting of PKA and phosphorylation of channel subunits
19. + pump current in ventricular myocytes from guinea pig heart
20. Electrophysiology of the sodium-potassium-ATPase in cardiac cells
21. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
22. Autonomic regulation of a chloride current in heart
23. Chloride current in mammalian cardiac myocytes. Novel mechanism for autonomic regulation of action potential duration and resting membrane potential
24. Chelerythrine is a potent and specific inhibitor of protein kinase C
25. Genistein increases the sensitivity of cardiac ion channels to β-adrenergic receptor stimulation
26. 2+ regulation in isolated ferret ventricular myocytes
27. Phosphorylation by protein kinase C is required for acute activation of cystic fibrosis transmembrane conductance regulator by protein kinase A
28. Na in guinea pig ventricular myocytes
29. 2+ channels by β-adrenergic agonists
30. Modulation of Ca current during the phosphorylation cycle in the guinea pig heart
31. Comparison of ouabain-sensitive and -insensitive Na/K pumps in HEK293 cells
32. + pump in guinea-pig ventricular myocytes
33. + pumps in guinea-pig ventricular myocytes
34. Distribution of active protein kinase C in smooth muscle
35. - channel function in guinea pig ventricular myocytes
36. [Na] and [K] dependence of the Na/K pump current-voltage relationship in guinea pig ventricular myocytes
37. - conductance in cardiac myocytes
38. 1-adrenergic inhibition of the β-adrenergically activated chloride current in guinea pig ventricular myocytes
39. Activation of adenylate cyclase by the diterpene forskolin does not require the guanine nucleotide regulatory protein
40. Competitive inhibition by diacylglycerol of specific phorbol ester binding
41. Synergistic activation of guinea-pig cardiac cystic fibrosis transmembrane conductance regulator by the tyrosine kinase inhibitor genistein and cAMP
42. Phorbol ester activation of chloride current in guinea-pig ventricular myocytes
43. 2+ conductances by (13R)-spiroforskolin
44. +-ATPase
45. Activation of a heart chloride current during stimulation of protein kinase C
46. Properties of a protein kinase C-activated chloride current in guinea pig ventricular myocytes
47. + pump current in guinea-pig ventricular myocytes
48. 2+ current mediated by pertussis toxin-sensitive G protein and cAMP-dependent protein kinase A in atrial myocytes
49. 1b-adrenoceptor-mediated stimulation of Na-K pump current in adult rat ventricular myocytes
50. Regulation of recombinant cardiac cystic fibrosis transmembrane conductance regulator chloride channels by protein kinase C
51. 2+ buffering in guinea pig ventricular cardiomyocytes
52. Protein kinase inhibitor H-89 reverses forskolin stimulation of cardiac L-type calcium current
53. - currents in feline ventricular myocytes
54. Association of cystic fibrosis transmembrane conductance regulator and protein phosphatase 2C