Gating kinetics and ligand sensitivity modified by phosphorylation of cardiac ryanodine receptors

Pflugers Archiv European Journal of Physiology

Volumn 444, Issue 1-2, 2002, Pages 202-212

  Uehara, Akira ^a   Yasukochi, Midori ^a   Mejía Alvarez, Rafael ^b   Fill, Michael ^b   Imanaga, Issei ^a  

^a FUKUOKA UNIVERSITY   (Japan)

^b LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

Lipid bilayers; Phosphorylation; Protein kinase; Ryanodine receptor; Sarcoplasmic reticulum

Indexed keywords

LIGAND; PROTEIN KINASE; RYANODINE RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BILAYER MEMBRANE; CALCIUM TRANSPORT; CHANNEL GATING; CLUSTER ANALYSIS; CONTROLLED STUDY; DEPHOSPHORYLATION; ENZYME PHOSPHORYLATION; HISTOGRAM; LIPID BILAYER; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SARCOPLASMIC RETICULUM; STEADY STATE;

ADENOSINE TRIPHOSPHATE; ALGORITHMS; ANIMALS; BIOTRANSFORMATION; CALCIUM; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DOGS; ENZYME INHIBITORS; ION CHANNEL GATING; KINETICS; LIGANDS; MEMBRANES; MYOCARDIUM; PHOSPHORYLATION; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOPLASMIC RETICULUM;

EID: 0036261225     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00424-002-0791-3     Document Type: Article

References (24)

1. Divalent cation activation and inhibition of single calcium release channels from sheep cardiac sarcoplasmic reticulum
2. 2+ sparks in cardiac muscle
3. Calcium sparks: Elementary events underlying excitation contraction coupling in heart muscle
4. Fitting and statistical analysis of single-channel records
5. Calculator programs for computing the composition of the solutions containing multiple metals and ligands used for experiments in skinned muscle cells
6. 2+ sparks in rat ventricular myocytes
7. Phosphorylation modulates the function of the calcium release channel of sarcoplasmic reticulum from cardiac muscle
8. Phosphorylation of the purified cardiac ryanodine receptor by exogenous and endogenous protein kinases
9. The cardiac sarcoplasmic reticulum calcium release channel: Modulation of ryanodine binding and single channel activity
10. Functional characterization of the ryanodine receptor purified from sheep cardiac muscle sarcoplasmic reticulum
11. 2+ release induced by flash photolysis of nitr-5
12. 2+-activated protease
13. 2+-release channel with monovalent cations as permeant species
14. Purified ryanodine receptor from rabbit skeletal muscle in the calcium-release channel of sarcoplasmic reticulum
15. Phosphorylation of the porcine skeletal and cardiac muscle sarcoplasmic reticulum ryanodine receptor
16. Phosphorylation of the cardiac ryanodine receptor by cAMP-dependent protein kinase
17. Regulation of the cardiac ryanodine receptor by protein kinase-dependent phosphorylation
18. Neutral carrier ion-selective microelectrodes for measurement of intracellular free calcium
19. Rectification of rabbit cardiac ryanodine receptor current by endogenous polyamines
20. Effect of sphingosylphosphorylcholine on the single channel gating properties of the cardiac ryanodine receptor
21. 2+ and phosphorylation
22. Unique phosphorylation site on the cardiac ryanodine receptor regulates calcium channel activity
23. Phosphorylation of ryanodine receptors in rat myocytes during beta-adrenergic stimulation
24. 2+ release channels