Pituitary corticotroph adenoma containing many apoptotic cells: A histologic, immunohistochemical, ultrastructural and molecular study

Ultrastructural Pathology

Volumn 26, Issue 1, 2002, Pages 27-32

  Messini, Irene ^a   Kontogeorgos, George ^a   Kovacs, Kalman ^a   Horvath, Eva ^a   Smyth, Harley S ^a  

^a KAT HOSPITAL   (Greece)

Author keywords

Adenoma; Apoptosis; Electron microscopy; Keratin; Pathology; Pituitary

Indexed keywords

CYTOKERATIN 18;

ADULT; APOPTOSIS; ARTICLE; CASE REPORT; CELL LABELING; CELL ULTRASTRUCTURE; CUSHING DISEASE; ELECTRON MICROSCOPY; FEMALE; HISTOPATHOLOGY; HUMAN; HYPOPHYSIS ADENOMA; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ADENOMA; ADRENOCORTICOTROPIC HORMONE; ADULT; APOPTOSIS; CUSHING SYNDROME; DNA, NEOPLASM; FEMALE; HUMANS; IMMUNOENZYME TECHNIQUES; IN SITU NICK-END LABELING; KI-67 ANTIGEN; PITUITARY NEOPLASMS; TUMOR MARKERS, BIOLOGICAL;

EID: 0036257859     PISSN: 01913123     EISSN: None     Source Type: Journal    
DOI: 10.1080/01913120252934305     Document Type: Article

References (18)

1. Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
2. The biochemistry of cell death by apoptosis
3. Apoptosis
4. Apoptosis in nontumorous and neoplastic human pituitaries
5. A new method to detect apoptosis in paraffin sections: In situ end-labeling of fragmented DNA
6. Apoptosis in human pituitary adenomas: A morphologic and in situ end-labeling study
7. Differentiation between cellular apoptosis and necrosis by the combined use of in situ tailing and nick translation techniques
8. In situ end labeling detects DNA strand breaks in apoptosis and other physiological and pathological states
9. Ultrastructural features of apoptosis in human pituitary adenomas
10. Bcl-2 gene family in endocrine pathology: A review
11. Caspase cleavage of keratin 18 and reorganization of intermediate filaments during epithelial apoptosis
12. α-Subunit immunoreactivity in plurihormonal adenomas of patients with acromegaly
13. Apoptosis in the anterior pituitary gland of the rat: Studies with estrogen and bromocriptine
14. Introduction of apoptosis in rat ACTH-secreting adenoma cells by bromocriptine
15. Apoptosis and p53 suppressor gene protein expression in human anterior pituitary adenomas
16. p53 expression in pituitary adenomas in carcinomas: Correlation with invasiveness and tumor growth fractions
17. Immunocytochemical accumulation of p53 in corticotroph adenomas: Relationship with heat-shock proteins and apoptosis
18. What is an apoptotic index measuring?