Friability of granules - Evaluation of different test methods

Pharmazeutische Industrie

Volumn 64, Issue 4, 2002, Pages 390-397

  Christiansen, Claudia ^a   Müller, Bernd W ^a  

^a UNIVERSITY OF KIEL   (Germany)

Author keywords

Friability testing methods; Granules; Pellets

Indexed keywords

ACETYLCYSTEINE; CITRIC ACID; CYCLAMATE SODIUM; GELATIN; GLYCEROL; LACTOSE; MAGNESIUM STEARATE; MICROCRYSTALLINE CELLULOSE; POVIDONE; SACCHARIN SODIUM; STARCH; SUCROSE;

AIR; ANALYTIC METHOD; ARTICLE; CRUSHING STRENGTH; DRUG GRANULE; DRUG PELLET; HARDNESS; INTERMETHOD COMPARISON; MECHANICAL STRESS; TABLET FRIABILITY;

EID: 0036256080     PISSN: 0031711X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Binder effectiveness for beads with high drug levels
2. Development of matrix controlled release beads by extrusion-spheronization technology using a statistical screening design
3. Effects of spheronization on some properties of uncoated and coated granules containing different kinds of fillers
4. Use of powdered cellulose for the production of pellets by extrusion/spheronization
5. Gerät zur bestimmung des abriebs von festen arzneiformen, insbesondere von pellets
6. Friability of granules
7. Determination of pellet friability by use of an air stream apparatus