A preliminary evaluation of neural network analysis for pharmacodynamic modeling of the dosing of the hydroxymethylglutaryl coenzyme A-reductase inhibitors simvastatin and atorvastatin

Clinical Therapeutics

Volumn 24, Issue 4, 2002, Pages 653-661

  Moon, Albert ^a   Smith, Timothy ^a  

^a UNIVERSITY OF THE PACIFIC   (United States)

Author keywords

Atorvastatin; HMG CoA reductase inhibitors; Hyperlipidemia; Neural networks; Pharmacodynamics; Simvastatin

Indexed keywords

ATORVASTATIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INSULIN; SIMVASTATIN;

ACCURACY; ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL PROTOCOL; COMPUTER PREDICTION; CONFIDENCE INTERVAL; CONTROLLED STUDY; CORRELATION ANALYSIS; DIABETES MELLITUS; DOSE CALCULATION; DOSE RESPONSE; EXPERIMENTAL MODEL; FEMALE; HEART INFARCTION; HUMAN; LIPID BLOOD LEVEL; MALE; NERVE CELL NETWORK; PHARMACODYNAMICS;

EID: 0036254753     PISSN: 01492918     EISSN: 1879114X     Source Type: Journal    
DOI: 10.1016/S0149-2918(02)85140-2     Document Type: Article

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