Autoantibody against, malondialdehyde-modified low density lipoprotein in patients with non-diabetic unstable angina: A potential role in immunologic reaction of plaque instability

Yonsei Medical Journal

Volumn 43, Issue 2, 2002, Pages 203-210

  Kwon, Kihwan ^a   Kwon, Hyuck Moon ^a   Hong, Bum Kee ^a   Kim, Dongsoo ^a   Lee, Ju Yong ^a   Ryu, Sung Kee ^a   Park, Byoung Eun ^a   Park, Hyun Young ^a   Kim, Jeong Ho ^a   Yoon, Young Won ^a   Cho, Seung Yun ^a   Kim, Hyun Seung ^a  

^a Yonsei University College of Medicine   (South Korea)

Author keywords

Atherosclerosis; Autoantibodies; Coronary artery disease; Oxidized LDL

Indexed keywords

AUTOANTIBODY; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; MALONALDEHYDE; OXIDIZED LOW DENSITY LIPOPROTEIN; TRIACYLGLYCEROL;

ACUTE HEART INFARCTION; ADULT; AGE; AGED; ANGIOGRAPHY; ANTIBODY BLOOD LEVEL; ANTIBODY TITER; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; BODY MASS; CLINICAL FEATURE; CONTROLLED STUDY; CORONARY ARTERY DISEASE; CORONARY ARTERY OBSTRUCTION; DIABETES MELLITUS; DISEASE ASSOCIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENDER; HEART MUSCLE ISCHEMIA; HUMAN; IMMUNE RESPONSE; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; MULTIPLE REGRESSION; OPTICAL DENSITY; SMOKING; SYMPTOM; UNSTABLE ANGINA PECTORIS;

EID: 0036252639     PISSN: 05135796     EISSN: None     Source Type: Journal    
DOI: 10.3349/ymj.2002.43.2.203     Document Type: Article

References (28)

1. Beyond cholesterol: Modification of low-density lipoprotein that increases its atherogenicity
2. Type I macrophage scavenger receptor contains alpha helical and collagen-like coiled coils
3. A delayed and sustained rise of cytosolic calcium is elicited by oxidized LDL in cultured bovine aortic endothelial cells
4. Oxidatively modified human low-density lipoprotein stimulates leukocyte adherence to the microvascular endothelium in vivo
5. Lysophosphatidylcholine plays an essential role in the mitogenic effect of oxidized LDL on murine macrophages
6. Low, density lipoprotein undergoes oxidative modification in vivo
7. Antiphospholipid antibodies are directed against epitopes of oxidized phospholipids: Recognition of cardiolipin by monoclonal antibodies to epitopes of oxidized low-density lipoprotein
8. Apoprotein E-deficient mice are a model of lipoprotein oxidation in atherogenesis: Demonstration of oxidation-specific epitopes in lesions and high titers of autoantibodies to malondialdehyde-lysine in serum
9. Cloning of monoclonal autoantibodies to epitopes of oxidized lipoproteins from apo E-deficient mice: Demonstration of epitopes of oxidized LDL in human plasma
10. Immunization of LDL receptordeficient rabbits with omologous malondialdehyde-modified LDL reduces atherogenesis
11. Immunization of LDL receptor- deficient mice with homologous malondialdehydemodified and native LDL educes progression of atherosclerosis by mechanisms other than induction of high titers of antibodies to oxidative neoepitopes
12. LDL oxidation in patients with severe carotid atherosclerosis: A study of in vivo oxidation markers
13. Anti-oxidized low-density lipoprotein antibodies in patients with coronary heart disease and normal healthy volunteers
14. Autoantibody against oxidized LDL and progression of carotid atherosclerosis
15. Autoantibodies against oxidized LDL do not predict atherosclerotic vascular disease in non-insulin-dependent diabetes mellitus
16. Transient reduction of autoantibodies against oxidized LDL in patients with acute myocardial infarction
17. Oxidized LDL and Malondialdehyde-modified LDL in patients with acute coronary syndromes and stable coronary artery disease
18. Monoclonal antibodies against oxidized low-density lipoprotein bind to apoptotic cells and inhibit their phagocytosis by elicited macrophages: Evidence that oxidation-specific epitopes mediate macrophage recognition
19. Protective effect of high-density lipoprotein associated paraoxonase: Inhibition of the biological activity of minimally oxidized low-density lipoprotein
20. Manlondialdehyde-modified LDL as a marker of acute coronary syndromes
21. Human-derived anti-Oxidized LDL autoantibody blocks uptake of oxidized LDL by macrophages and localizes to atherosclerotic lesions in vivo
22. Different populations of macrophages use either the vitronectin receptor or the phosphatidylserine receptor to recognize and remove apoptotic cells
23. Specific contribution of different phospholipid surfaces to the activation of prothrombin by the fully assembled prothrombinase
24. Expression of tissue factor procoagulant activity: Regulation by cytosolic calcium
25. Current Perspective on the Role of Apoptosis in Atherothrombotic Disease
26. Protection of low-density lipoprotein against oxidative modification by high-density lipoprotein associated paraoxonase
27. Smoking Increases Tissue Factor Expression in Atherosclerotic Plaques: Implications for Plaque Thrombogenicity
28. Smoking Is Associated With Reduced Serum Paraoxonase Activity and Concentration in Patients With Coronary Artery Disease