A randomized controlled trial to evaluate the slow-acting symptom modifying effects of a regimen containing colchicine in a subset of patients with osteoarthritis of the knee

Osteoarthritis and Cartilage

Volumn 10, Issue 4, 2002, Pages 247-252

  Das, S K ^a   Mishra, K ^a   Ramakrishnan, S ^a   Srivastava, R ^a   Agarwal, G G ^b   Singh, R ^a   Sircar, A R ^a  

^a KING GEORGE'S MEDICAL UNIVERSITY   (India)

^b UNIVERSITY OF LUCKNOW   (India)

Author keywords

Colchicine; CPPD crystals; Inflammation; Osteoarthritis

Indexed keywords

AMINOTRANSFERASE; ANALGESIC AGENT; C REACTIVE PROTEIN; CALCIUM PYROPHOSPHATE; COLCHICINE; CORTICOSTEROID; CREATININE; HEMOGLOBIN; METHYLPREDNISOLONE ACETATE; NONSTEROID ANTIINFLAMMATORY AGENT; PIROXICAM; PLACEBO; PROTEIN; RHEUMATOID FACTOR; STARCH; STEROID; URIC ACID;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG RESPONSE; DRUG SAFETY; DRUG TOLERABILITY; DYSPEPSIA; FEMALE; HUMAN; INFLAMMATION; KNEE OSTEOARTHRITIS; MALE; MANTEL HAENSZEL TEST; MOTOR DYSFUNCTION; MULTIVARIATE ANALYSIS; MYALGIA; PAIN ASSESSMENT; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RISK ASSESSMENT; SYMPTOMATOLOGY; UPPER RESPIRATORY TRACT INFECTION; VISUAL ANALOG SCALE;

EID: 0036251197     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1053/joca.2002.0516     Document Type: Article

References (18)

1. Synovial inflammation, crystals and OA
2. Calcium pyrophosphate crystals deposition in hyaline cartilage: Ultra structural analysis and implications for pathogenesis
3. Chondrocalcinosis and rapid destruction of the hip
4. Autopsy study correlating degree of osteoarthritis, synovitis and evidence of articular calcification
5. Pathology of Osteoarthritis
6. A preliminary clinical trial to assess short term symptom modifying effect of a regimen containing colchicine in a selected subset of patients with osteoarthritis knee
7. Submicroscopic crystals in osteoarthritic synovial fluids
8. Development of criteria for the classification and reporting of osteoarthritis: Classification of osteoarthritis of the knee
9. KGMC index-a modified WOMAC index to evaluate response in Indian patients with osteoarthritis knee
10. Validation study of WOMAC: A health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee
11. An articular index for the assessment of osteoarthritis
12. To study the prevalence of chondrocalcinosis and calcium pyrophosphate dihydrate crystals in the patients with symptomatic osteoarthritis knee
13. Measurement of patient outcome in arthritis
14. Synovial fluid crystals in osteoarthritis
15. Calcium pyrophosphate crystal deposition disease, pseudogout, articular chondrocalcinosis
16. Intra-articular corticosteroid treatment in osteoarthritis
17. Does colchicine work? The results of the first controlled study in acute gout
18. Colchicine: 1998 update