Aponecrotic, antiangiogenic and antiproliferative effects of a novel dextran derivative on breast cancer growth in vitro and in vivo

British Journal of Pharmacology

Volumn 135, Issue 8, 2002, Pages 1859-1871

  Benedetto, Mélanie Di ^a   Starzec, Anna ^a   Colombo, Bruno M ^a   Briane, Dominique ^a   Perret, Gérard Y ^a   Kraemer, Michel ^a   Crépin, Michel ^b  

^a UNIVERSITÉ PARIS 13   (France)

^b SAINT LOUIS HOSPITAL   (France)

Author keywords

Angiogenesis; Antitumour activity; Carboxymethyl benzylamide dextran (CMDB); Phenylacetate carboxymethyl benzylamide dextran (NaPaC); Sodium phenylacetate (NaPa)

Indexed keywords

CARBOXYMETHYL BENZYLAMIDE DEXTRAN; DEXTRAN DERIVATIVE; GROWTH FACTOR; PHENYLACETATE CARBOXYMETHYL BENZYLAMIDE DEXTRAN; PHENYLACETATE SODIUM; PHENYLACETIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER GROWTH; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL DEATH; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA REPLICATION; DRUG EFFECT; DRUG POTENCY; ESTERIFICATION; HUMAN; IC 50; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR VOLUME;

3T3 CELLS; ANGIOGENESIS INHIBITORS; ANIMALS; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CULTURE MEDIA, CONDITIONED; DEXTRANS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; FEMALE; GROWTH INHIBITORS; HUMANS; MICE; MICE, INBRED BALB C; MICE, NUDE; NECROSIS; PHENYLACETATES; TUMOR CELLS, CULTURED; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 0036250348     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704645     Document Type: Article

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