Polyisoprenylated Benzophenones in Cuban Propolis; Biological Activity of Nemorosone

Zeitschrift fur Naturforschung - Section C Journal of Biosciences

Volumn 57, Issue 3-4, 2002, Pages 372-378

  Cuesta Rubio, Osmany ^a   Frontana Uribe, Bernardo A ^b   Ramirez Apan, Teresa ^b   Cardenas, Jorge ^b  

^a INSTITUTO DE FARMACIA Y ALIMENTOS   (Cuba)

^b UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

APIS MELLIFERA; CLUSIA ROSEA;

BENZOPHENONE DERIVATIVE; NEMOROSONE; PROPOLIS;

ANIMAL; ARTICLE; BEE; CELL CULTURE; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM TUMOR; CHEMISTRY; CONFORMATION; CUBA; DRUG EFFECT; HELA CELL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; ISOLATION AND PURIFICATION; MALE; PROSTATE TUMOR; PROTEIN PROCESSING; SQUAMOUS CELL CARCINOMA;

ANIMALS; BEES; BENZOPHENONES; CARCINOMA, SQUAMOUS CELL; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM NEOPLASMS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CUBA; HELA CELLS; HUMANS; MALE; MOLECULAR CONFORMATION; PROPOLIS; PROSTATIC NEOPLASMS; PROTEIN ISOPRENYLATION; TUMOR CELLS, CULTURED;

EID: 0036249452     PISSN: 09395075     EISSN: None     Source Type: Journal    
DOI: 10.1515/znc-2002-3-429     Document Type: Article

References (18)

1. Bankova V., Popov S., Bocari G. and Haxhialushi E. (1994), Phenolics in Albanian poplar buds and their relationship to propolis. Fitoterapia 65, 326-330.
2. Bisse J. (1988), Arboles de Cuba, Editorial Cientificotecnica, La Habana, Cuba.
3. Blount J. F. and Williams T. H. (1976), Revised structure of xanthochymol. Tetrahedron Lett. 34, 2921-2924.
4. Cordell G. A., Kinghorn A. D. and Pezzuto J. M. (1993), Separation, structure elucidation and bioassay of cytotoxic natural products, In: Bioactive Natural Products: Detection, Isolation and Structure Determination, Colegate S. M. and Molyneux R. J. Eds. CRC Press, Boca Raton, USA, 199-200.
5. Cottele N., Bernier J. L., Catteau J. P., Pommery P., Wallet J. C. and Gaydou E. M. (1996), Antioxidant properties of hydroxy-flavones. Free Radical Biol. and Med. 20, 35-43.
6. Cuesta O., Cuellar C. A., Rojas N., Velez C. H., Rastrelli L. and Aquino R. (1999), A polyisoprenylated benzo-phenone from Cuban propolis. J. Nat. Prod. 62, 1013-1015.
7. Cuesta-Rubio O., Velez-Castro H., Frontana-Uribe B. A. and Cardenas J. (2001), Nemorosone the major constituent of floral resins of Clusia rosea. Phytochemistry 57, 279-283.
8. De Oliveira C. M. A., Porto A. L. M., Bittrich V., Ven-cato I. and Marsaioli A. J. (1996), Floral resins of Clusia spp.: Chemical and biological function. Tetrahedron Lett. 37, 6427-6430.
9. De Oliveira C. M. A., Porto A. L. M., Bittrich V. and Marsaioli A. J. (1999), Two Polyisoprenylated benzo-phenones from the floral resins of three Clusia species. Phytochemistry 50, 1073-1079.
10. Gonzalez E. and Orzaez M. T. (1997), Estudio del pro-poleo: origen e importancia de los compuestos feno-licos en su composition. Alimentaria 283, 103-107.
11. Greenaway W., Scaysbrook T. and Whatley F. R. (1988), Composition of propolis in Oxfordshire U. K. and its relation to poplar bud exudates. Z. Naturforsch 43c, 301-304.
12. Gustafson K. R., Blunt J. W., Munro M. H. G., Fuller R. W., McKee T. C., Cardellina J. H., McMahon J. B., Cragg G. M. and Boyd M. R. (1992), The guttiferones, HIV-inhibitory benzophenones from Symphonia globulifera, Garcinia livingstonei, Garcinia ovalifolia and Clusia rosea. Tetrahedron 48, 10093-10102.
13. Kurkin V. A., Braslavsky V. B. and Zapesochnaya G. G. (1992), Determination of flavonoids in propolis. Far-matsiya 41, 35-39.
14. Lokvam J., Braddock J. F., Reichardt P. B. and Clausen T. P. (2000), Two polyisoprenylated benzophenones from the trunk latex of Clusia grandiflora (Clusia-ceae). Phytochemistry 55, 29-34.
15. Marcucci M. C. (1995), Propolis: chemical composition, biological properties and therapeutic activity. Apidologie 26, 83-99.
16. Marcucci M. C., Ferreres F., Custodio A. R., Ferreira M. M. C., Bankova V. S., García-Viguera C. and Bretz W. A. (2000), Evaluation of phenolic compounds in Brazilian propolis from different geographic regions. Z. Naturforsch. 55c, 76-81.
17. Monks A., Scudeiro D., Skehan P., Shoemaker R., Paull K., Vistica D., Hose C., Langley J., Cronise P., Vaigro-Wolff A., Gray-Goodrich M., Campbell H., Mayo J. and Boyd M. (1991), Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines. J. Natl. Cancer Inst. 83, 757-766.
18. Tomas-Barberan F. A., Garcia-Viguera C., Vit-Oliver P., Ferreres F. and Tomas-Lorente F. (1993), Phytochemical evidence for the botanical origin of tropical propolis from Venezuela. Phytochemistry 34, 191-196.