Platelet function testing in apheresis products: Flow cytometric, resonance thrombographic (RTG) and rotational thrombelastographic (roTEG) analyses

Transfusion and Apheresis Science

Volumn 26, Issue 3, 2002, Pages 147-155

  Gutensohn, K ^a   Geidel, K ^a   Kroeger, N ^a   Eifrig, B ^a   Crespeigne, N ^b   Kuehnl, P ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b Baxter R and D Europe   (Belgium)

Author keywords

Flow cytometry; Platelets; Resonance thrombography; Rotational thrombelastography; Storage

Indexed keywords

ANTIGEN; CD42 ANTIGEN; CD63 ANTIGEN; FIBRIN; FIBRINOGEN RECEPTOR; PADGEM PROTEIN; THROMBOCYTE CONCENTRATE; UNCLASSIFIED DRUG;

AGONIST; ANALYTIC METHOD; ARTICLE; BLOOD CLOTTING PARAMETERS; BLOOD CLOTTING TIME; CELL ASSAY; CELL SEPARATION; CONTROLLED STUDY; DEVICE; FEMALE; FLOW CYTOMETRY; HEMOSTASIS; HUMAN; HUMAN CELL; IMMUNOLOGICAL TECHNIQUE; IMMUNOREACTIVITY; MALE; NORMAL HUMAN; QUALITY CONTROL; REACTION TIME; RESONANCE THROMBOGRAPHY; STORAGE; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOCYTE FUNCTION; THROMBOCYTE RICH PLASMA; THROMBOCYTE STRUCTURE; THROMBOCYTOPHERESIS; THROMBOELASTOGRAPHY; BLOOD CLOTTING TEST; BLOOD STORAGE; COMPARATIVE STUDY; EVALUATION; INSTRUMENTATION; METHODOLOGY; STANDARD;

BLOOD COAGULATION TESTS; BLOOD PRESERVATION; FLOW CYTOMETRY; HUMANS; PLATELET ACTIVATION; PLATELET AGGREGATION; PLATELET FUNCTION TESTS; PLATELETPHERESIS; QUALITY CONTROL; THROMBELASTOGRAPHY;

EID: 0036248007     PISSN: 14730502     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1473-0502(02)00007-1     Document Type: Article

References (49)

1. Blood banking in the United States - 1981
2. Collection and transfusion of blood in the United States 1982-1988
3. Current trends in platelet transfusion - transfusion practices in Europe
4. Changes in platelet membrane glycoproteins during blood bank storage
5. In vitro platelet interactions in whole human blood exposed to biomaterial surfaces: Insights in blood compatibility
6. Biomaterials for blood-contacting applications
7. Activation during preparation and storage of platelet concentrates
8. In vitro assessment of the quality of stored platelet concentrates
9. Initial validation and quality control of platelet concentrates prepared by apheresis
10. Flow cytometry: A clinical test of platelet function
11. Flow cytometric analysis of platelet membrane antigens during and following continuous-flow plateletpheresis
12. Flow cytometric detection of activated platelets: Comparison of determining shape change, fibrinogen binding, and P-selectin expression
13. Occupancy of an adhesive glycoprotein receptor modulates expression of an antigenic site involved in cell adhesion
14. Studies of fibrinogen binding to platelets by flow cytometry: An improved method for studies of platelet activation
15. Platelet transfusion therapy for the cancer patient
16. Platelet transfusion therapy
17. Improving the quality of stored platelets
18. Detection of activated platelets in whole blood using activation-dependent monoclonal antibodies and flow cytometry
19. Applications of flow cytofluorometry to transfusion science
20. Flow cytometry in modern transfusion medicine
21. Platelet membrane glycoproteins
22. Platelet GPIb-V-IX complex. Structure, function, physiology, and pathology
23. Progressive platelet activation with storage: Evidence for shortened survival of activated platelets after transfusion
24. Detection and significance of alpha granule membrane protein 140 expression on platelets collected by apheresis
25. Cytoadhesins, integrins, and platelets
26. PADGEM protein: A receptor that mediates the interaction of activated platelets with neutrophils and monocytes
27. Purification of glycoproteins IIb and III from human platelet membranes and characterization of a calcium-dependent glycoprotein IIb-IIIa complex
28. Glycoprotein Ib and glycoprotein IX are fully complexed in the intact platelet membrane
29. Biocompatibility of a new cell separator studied by flow cytometry: Analyses of platelet antigens during apheresis and storage
30. Aspects of platelet storage
31. Improvement of platelet storage conditions by using new polyolefin containers
32. Prevention of leakage of di (2-ethylhexyl) phthalate from blood bags by glow discharge treatment and its effect on aggregability of stored platelets
33. The platelet storage lesion: Possible role of plasticizers
34. The role of flow cytometry in improving biocompatibility in transfusion medicine
35. Platelet aggregation
36. Stored human platelets retain full aggregation potential in response to pairs of aggregating agents
37. Exposure of fibrinogen receptors of fresh and stored platelets by ADP and epinephrine as single agents and as a pair
38. Platelet activation during preparation and storage of concentrates: Detection by flow cytometry
39. Evaluation of platelet function by flow cytometric measurement of ligand binding
40. Platelet storage at 22°C: Metabolic, morphologic, and functional studies
41. 5-day storage of single-donor platelets obtained using a blood cell separator
42. Platelet activation and its detection during the preparation of platelets for transfusion
43. Blutgerinnungsstudien mit der Thrombelastographie, einem neuen Untersuchungsverfahren
44. In vitro assessment of platelet function
45. Differenzierung der Therapie von Gerinnungsstörungen durch Diagnostik mit dem Resonanzthrombographen
46. Platelet activation may explain the storage lesion in platelet concentrates
47. Modulation of platelet surface adhesion receptors during cardiopulmonary bypass