Effects of cysteine on the pharmacokinetics of intravenous chlorzoxazone in rats with protein-calorie malnutrition

Biopharmaceutics and Drug Disposition

Volumn 23, Issue 3, 2002, Pages 121-129

  Kim, Yoon G ^a   Cho, Min K ^a   Kwon, Jong W ^b   Kim, Sang G ^a   Chung, Suk J ^a   Shim, Chang K ^a   Lee, Myung G ^a  

^a Seoul National University   (South Korea)

^b Dong A Pharmaceutical Company   (South Korea)

Author keywords

Chlorzoxazone and 6 hydroxychlorzoxazone; CYP2E1; PCM and PCMC; Pharmacokinetics; Rats

Indexed keywords

6 HYDROXYCHLORZOXAZONE; AZOSEMIDE; CHLORZOXAZONE; CYSTEINE; CYTOCHROME P450; CYTOCHROME P450 2E1; DOXORUBICIN; DRUG METABOLITE; MESSENGER RNA; PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DISTRIBUTION VOLUME; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG HALF LIFE; DRUG HYDROXYLATION; DRUG METABOLISM; DRUG TISSUE LEVEL; DRUG URINE LEVEL; ENZYME ACTIVITY; MALE; NONHUMAN; PLASMA PROTEIN BINDING; PROTEIN CALORIE MALNUTRITION; PROTEIN EXPRESSION; RAT; STEADY STATE; SUPPLEMENTATION; TISSUE DISTRIBUTION; URINARY EXCRETION;

ANIMALS; AREA UNDER CURVE; CHLORZOXAZONE; CYSTEINE; EATING; INJECTIONS, INTRAVENOUS; MALE; ORGAN SIZE; PROTEIN-ENERGY MALNUTRITION; RATS; RATS, SPRAGUE-DAWLEY; TISSUE DISTRIBUTION; WEIGHT GAIN;

EID: 0036245439     PISSN: 01422782     EISSN: None     Source Type: Journal    
DOI: 10.1002/bdd.300     Document Type: Article

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