Treatment of severe thrombocytopenia with IL-11 in children with Wiskott-Aldrich syndrome

Journal of Pediatric Hematology/Oncology

Volumn 24, Issue 4, 2002, Pages 323-326

  Braithwaite, Kiery ^a   Abu Ghosh, Amal ^a   Anderson, Lauren ^a   Cairo, Mitchell S ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Bone marrow transplantation; IL 11; Platelets; Stem cell transplantation; Thrombocytopenia; Wiskott Aldrich syndrome

Indexed keywords

INTERLEUKIN 11; RECOMBINANT INTERLEUKIN 11;

ARTICLE; BLEEDING; BONE MARROW TRANSPLANTATION; CASE REPORT; DRUG EFFICACY; DRUG SAFETY; GRAFT FAILURE; HUMAN; INFANT; MALE; PRIORITY JOURNAL; STEM CELL TRANSPLANTATION; THROMBOCYTE COUNT; THROMBOCYTE TRANSFUSION; THROMBOCYTOPENIA; WISKOTT ALDRICH SYNDROME;

CHILD, PRESCHOOL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; INFANT; INTERLEUKIN-11; MALE; PLATELET COUNT; THROMBOCYTOPENIA; WISKOTT-ALDRICH SYNDROME;

EID: 0036245223     PISSN: 10774114     EISSN: None     Source Type: Journal    
DOI: 10.1097/00043426-200205000-00022     Document Type: Article

References (23)

1. Familiarer, angeborener Morbus werhoffi?
2. Pedigree demonstrating a sex-linked recessive condition characterized by draining ears, eczematoid dermatitis and bloody diarrhea
3. Wiskott-Aldrich syndrome. An immunologic deficiency disease involving the afferent limb of immunity
4. The Wiskott-Aldrich syndrome in the United States and Canada (1892-1979)
5. Wiskott-Aldrich syndrome: Qualitative platelet defects and short platelet survival
6. A multiinstitutional survey of the Wiskott-Aldrich syndrome
7. Molecular cloning of a cDNA encoding interleukin 11, a stromal cell-derived lymphopoietic and hematopoietic cytokine
8. Recombinant human interleukin-11 stimulates megakaryocytopoiesis and increases peripheral platelets in normal and splenectomized mice
9. Effect of interleukin-11 with and without granulocyte colony- stimulating factor on in vivo neonatal rat hematopoiesis: Induction of neonatal thrombocytosis by interleukin-11 and synergistic enhancement of neutrophilia by interleukin-11 + granulocyte colony-stimulating factor
10. A randomized placebo-controlled trial of recombinant human interleukin-11 in cancer patients with severe thrombocytopenia due to chemotherapy
11. Clinical and hematological recovery in children with recurrent/refractory solid tumors treated with ifosfamide, carboplatin, and etoposide (ICE) followed by sequential trials of IL-11/G-CSG, IL-6/G-CSF, IL-6/G-CSF, PIXY321, or G-CSF: Children's Cancer Group (CCG) and Genetics Institute experience
12. A bone marrow stromal-derived growth factor, interleukin-11, stimulates recovery of small intestinal mucosal cells after cytoablative therapy
13. Bone marrow transplantation in 26 patients with Wiskott-Aldrich syndrome from a single center
14. Marrow transplantation from human leukocyte antigen-identical or haploidentical donors for correction of Wiskott-Aldrich syndrome
15. Complete correction of the Wiskott-Aldrich syndrome by allogeneic bone- marrow transplantation
16. Successful transplantation of HLA-matched and HLA-mismatched umbilical cord blood from unrelated donors: Analysis of engraftment and acute graft-versus-host disease
17. Leukocyte reduction and ultraviolet B irradiation of platelets to prevent alloimmunization and refractoriness to platelet transfusions
18. Decreased incidence of marrow graft rejection in patients with severe aplastic anemia: Changing impact of risk factors
19. Growth of gram-positive and gram-negative bacteria in platelet concentrates
20. Delay in platelet recovery after bone marrow transplantation: Impact of cytomegalovirus infection
21. Molecular cloning of two isoforms of a receptor for the human hematopoietic cytokine interleukin-11
22. The thrombocytopenia of Wiskott Aldrich syndrome is not related to a defect in proplatelet formation
23. Differential mechanisms in the regulation of endogenous levels of thrombopoietin and interleukin-11 during thrombocytopenia: Insight into the regulation of platelet production