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Volumn , Issue 5, 2002, Pages 1035-1039

cis-[PtCL2(NH3){2-(2-hydroxyethyl)pyridine}] - An analogue of the anticancer drug AMD473: Unusual hydrolysis rates and pKa values for the diaqua adduct

(8) Hotze, Anna C G a Chen, Yu a Hambley, Trevor W b Parsons, Simon a Kratochwil, Nicole A a Parkinson, John A a Munk, Vivienne P a Sadler, Peter J a

a UNIVERSITY OF EDINBURGH (United Kingdom)

b UNIVERSITY OF SYDNEY (Australia)

Author keywords

Antitumor agents; Hydrolysis; Molecular modelling; Platinum

Indexed keywords

CRYSTAL STRUCTURE; MOLECULAR MODELING; PLATINUM; PLATINUM COMPOUNDS; PYRIDINE;

2-PICOLINE; ANTICANCER DRUG; ANTITUMOUR AGENTS; AQUATION; HYDROLYSIS RATE; STRUCTURAL FEATURE; X RAY CRYSTAL STRUCTURES;

HYDROLYSIS;

AMMINEDICHLORO(2 METHYLPYRIDINE)PLATINUM; AMMINEDICHLORO[2 (2 HYDROXYETHYL)PYRIDINE]PLATINUM; ANTINEOPLASTIC AGENT; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CHEMICAL REACTION KINETICS; CRYSTAL STRUCTURE; DRUG HYDROLYSIS; DRUG STRUCTURE; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PH; PKA; REACTION ANALYSIS; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

EID: 0036242228 PISSN: 14341948 EISSN: None Source Type: Journal
DOI: 10.1002/1099-0682(200205)2002:5<1035::AID-EJIC1035>3.0.CO;2-I Document Type: Article

Times cited : (30)

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