Functional residual capacity (FRC) does not predict response to surfactant in preterm infants

American Journal of Perinatology

Volumn 19, Issue 3, 2002, Pages 155-162

  Dermendjian, Mariette ^a   Varma, Swati ^a   Krauss, Alfred N ^a   Auld, Peter A M ^a  

^a WEILL CORNELL MEDICAL CENTER   (United States)

Author keywords

Arterial alveolar PO2 ratio; FRC; Hyaline membrane disease; Preterm infants; Surfactant replacement

Indexed keywords

LUNG SURFACTANT EXTRACT; SURFACTANT;

ARTERIAL OXYGEN SATURATION; ARTICLE; CLINICAL ARTICLE; FEMALE; FUNCTIONAL RESIDUAL CAPACITY; HUMAN; HYALINE MEMBRANE DISEASE; INFANT; LUNG COMPLIANCE; LUNG DEVELOPMENT; MALE; PREMATURITY; PRIORITY JOURNAL; RESPIRATORY DISTRESS SYNDROME; TREATMENT OUTCOME;

BIOLOGICAL PRODUCTS; BLOOD GAS ANALYSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FUNCTIONAL RESIDUAL CAPACITY; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; LUNG; MALE; PREDICTIVE VALUE OF TESTS; PULMONARY SURFACTANTS; TREATMENT OUTCOME;

EID: 0036239898     PISSN: 07351631     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2002-25314     Document Type: Article

References (27)

1. Surface properties in relation to atelectasis and hyaline membrane disease
2. Measurement of thoracic gas volume in the newborn infant
3. Static volume-pressure relations of excised lungs of infants with hyaline membrane disease of the newborn infant
4. Normal and abnormal expansion of the lungs of newborn infants obtained at autopsy: II. Opening pressure, maximal volume, and stability of expansion
5. Studies of respiratory physiology in the newborn infant: Observations during and after respiratory distress
6. Serial studies of lung volume and VA/Q in hyaline membrane disease
7. Measurement of functional residual capacity in distressed neonates by helium rebreathing
8. Double-blind clinical trial of calf lung surfactant extract for the prevention of hyaline membrane disease in extremely premature infants
9. Surfactant replacement therapy at birth: Final analysis of a clinical trial and comparison with similar trials
10. Improved outcome at 28 days of age for very low birth weight infants treated with a single dose of a synthetic surfactant
11. Randomized, placebo-controlled trial of human surfactant given at birth versus rescue administration in very low birth weight infants
12. Effects of two rescue doses of a synthetic surfactant on mortality rate and survival without bronchopulmonary dysplasia in 700- to 1350-gram infants with respiratory distress syndrome
13. Factors associated with surfactant treatment response in infants with severe respiratory distress syndrome
14. Prediction of the acute response to surfactant by pulmonary function testing
15. Pulmonary gas trapping in premature infants
16. The arterial/alveolar oxygen tension ratio: An index of gas exchange applicable to varying inspired oxygen concentrations
17. Ventilation-perfusion relationships in preterm infants after surfactant treatment
18. Surfactant improves gas mixing and alveolar ventilation in preterm lambs
19. Natural surfactant instilled in premature lambs increases lung volume and improves ventilation homogeneity within five minutes
20. Surfactant replacement therapy in surfactant deficient rabbits: Early effects on lung function and biochemical aspects
21. The physiologic effects of surfactant treatment on gas exchange in newborn premature infants with hyaline membrane disease
22. Immediate effects on lung function of instilled human surfactant in mechanically ventilated newborn infants with IRDS
23. Ventilation-perfusion relationship and its role in alveolar gas exchange
24. Ventilation-perfusion abnormalities in the premature infant: Triple gradient
25. Ventilation-perfusion abnormalities in the preterm infant with hyaline membrane disease: A two-compartment model of the neonatal lung