Pharmacokinetic parameters of ciprofloxacin (500 mg/5 mL) oral suspension in critically ill patients with severe bacterial pneumonia: A comparison of two Dosages

Journal of Chemotherapy

Volumn 14, Issue 2, 2002, Pages 175-180

  Debon, R ^a   Breilh, D ^a   Boselli, Emmanuel ^a   Saux, M C ^a   Duflo, F ^a   Chassard, D ^a   Allaouchiche, B ^a  

^a HÔTEL DIEU   (France)

Author keywords

Ciprofloxacin; Nasogastric delivery of antibiotic; Pharmacodynamic; Pharmacokinetics; Pneumonia treatment

Indexed keywords

CIPROFLOXACIN;

AREA UNDER THE CURVE; ARTICLE; ARTIFICIAL VENTILATION; BACTERIAL PNEUMONIA; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COST CONTROL; CRITICAL ILLNESS; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG RELEASE; ENTERIC FEEDING; FEMALE; HUMAN; MALE; NASOGASTRIC TUBE; NONHUMAN; PHARMACODYNAMICS; PSEUDOMONAS AERUGINOSA; RANDOMIZED CONTROLLED TRIAL; STAPHYLOCOCCUS AUREUS; STEADY STATE; SUSPENSION;

EID: 0036239477     PISSN: 1120009X     EISSN: None     Source Type: Journal    
DOI: 10.1179/joc.2002.14.2.175     Document Type: Article

References (15)

1. Clinical and economic evaluation of oral ciprofloxacin after an abbreviated course of intravenous antibiotics
2. Pharmacokinetics of ciprofloxacin: Intravenous and increasing oral doses
3. A laboratory assessment of ciprofloxacin and comparable antimicrobial agents
4. Enteric absorption of ciprofloxacin during tube feeding in the critically ill
5. Bioavailability of ciprofloxacin after multiple enteral and intravenous doses in ICU patients with severe gram-negative intraabdominal infections
6. Oral bioequivalence of three ciprofloxacin formulations following single-dose administration: 500 mg tablet compared with 500 mg/10 mL or 500 mg/5 mL suspension and the effect of food on the absorption of ciprofloxacin oral suspension
7. A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study
8. A critical appraisal of chromatographic and immunoassay techniques for clinical drug analysis
9. Symbols in pharmacokinetics
10. Pharmacokinetic profiles of ciprofloxacin after single intravenous and oral doses
11. The use of in vitro pharmacodynamic models of infection to optimize fluoroquinolone dosing regimens
12. The inhibitory quotient - A method for interpreting minimum inhibitory concentration data
13. Pharmacokinetics and absolute bioavailability of ciprofloxacin administered through a nasogastric tube with continuous enteral feeding to critically ill patients
14. Pharmacodynamics of intravenous ciprofloxacin in seriously ill patients
15. Enteric absorption of ciprofloxacin during the immediate postoperative period