Non-invasive determination of the paternal HLA haplotype of a fetus using kinetic PCR to detect fetal microchimerism in maternal plasma

Bone Marrow Transplantation

Volumn 29, Issue 6, 2002, Pages 527-529

  Reed, W ^a   Kong, D Z ^a   Lee, T H ^a   Cowan, M J ^a   Busch, M P ^a   Baxter Lowe, L A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cord blood; Kinetic PCR; Microchimerism; Prenatal diagnosis; Prenatal HLA typing; Real time PCR; Transplantation

Indexed keywords

DNA; HLA A ANTIGEN; HLA B ANTIGEN; HLA DR ANTIGEN; PRIMER DNA;

ACUTE LEUKEMIA; ALLELE; ARTICLE; BLOOD BANK; BLOOD DONOR; BLOOD GROUP TYPING; CASE REPORT; DNA ISOLATION; FEMALE; HAPLOTYPE; HLA TYPING; HUMAN; MATERNAL PLASMA; MICROCHIMERISM; NON INVASIVE MEASUREMENT; PATERNITY TEST; POLYMERASE CHAIN REACTION; PRENATAL SCREENING; PRESCHOOL CHILD; PRIORITY JOURNAL; SIBLING; TRANSPLANTATION; UMBILICAL CORD BLOOD;

EID: 0036237659     PISSN: 02683369     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bmt.1703411     Document Type: Article

References (12)

1. Prenatal HLA-matching to determine suitability for allogeneic bone marrow transplantation
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3. Fetal DNA in maternal plasma: Biology and diagnostic applications
4. Survival of donor leukocyte subpopulations in immunocompetent transfusion recipients: Frequent long-term microchimerism in severe trauma patients
5. Detection of microchimerism by PCR is a function of amplification strategy
6. Male fetal progenitor cells persist in maternal blood for as long as 27 years postpartum
7. Kinetics of fetal cellular and cell-free DNA in the maternal circulation during and after pregnancy: Implications for non-invasive prenatal diagnosis
8. Presence of fetal DNA in maternal plasma and serum
9. Rapid clearance of fetal DNA from maternal plasma
10. Sibling donor cord blood banking for children with sickle cell disease
11. Collection of sibling donor cord blood for children with thalassemia